The ocular delivery of drugs encounters several limitations because of the dynamic and
static barriers of the human's eye anatomy and physiology. The poor bioavailability of drugs …

Glaucoma is one of the leading causes of irreversible blindness worldwide. It is
characterized by progressive optic neuropathy in association with damage to the optic nerve …

Ocular hypertension is a major risk factor for the development and progression of glaucoma.
Frequent and long-term application of latanoprost often causes undesirable local side …

Glaucoma is an irreversible ocular disease that may lead to progressive visual field loss and
eventually to blindness with inadequately controlled intraocular pressure (IOP). Latanoprost …

Topical medication remains the first line treatment of glaucoma; however, sustained ocular
drug delivery via topical administration is difficult to achieve. Most drugs have poor …

Purpose: To determine whether latanoprost, a prostaglandin analog proven to be very
effective in reducing intraocular pressure (IOP) in humans, can also slow myopia …

Current management of glaucoma entails the medical, laser, or surgical reduction of
intraocular pressure (IOP) to a predetermined level of target IOP, which is commensurate …

Poor bioavailability of topically instilled drug is the major concern in the field of ocular drug
delivery. Efflux transporters, static and dynamic ocular barriers often possess rate limiting …

Highlights•Mitochondrial function can be enhanced to attenuate glaucoma and other
neuronal degenerating diseases with the use, for example, of red light.•Targeting neuronal …

The treatment of glaucoma in and around pregnancy offers the unique challenge of
balancing the risk of vision loss to the mother as against the potential harm to the fetus or …