▪ Abstract Comparative modeling predicts the three-dimensional structure of a given protein
sequence (target) based primarily on its alignment to one or more proteins of known …

Toll-like receptors (TLRs) are a family of pattern recognition receptors that are an important
link between innate and adaptive immunity. Many vaccines incorporate ligands for TLRs as …

Genome sequencing projects have resulted in a rapid increase in the number of known
protein sequences. In contrast, only about one-hundredth of these sequences have been …

Comparative protein structure modeling predicts the three‐dimensional structure of a given
protein sequence (target) based primarily on its alignment to one or more proteins of known …

We describe a comparative protein modelling method designed to find the most probable
structure for a sequence given its alignment with related structures. The three dimensional …

Publisher Summary Functional characterization of a protein sequence is one of the most
frequent problems in biology. This task is usually facilitated by accurate three-dimensional …

Genome sequencing projects have resulted in a rapid increase in the number of known
protein sequences. In contrast, only about one-hundredth of these sequences have been …

Background Increased secretion of growth hormone leads to gigantism in children and
acromegaly in adults; the genetic causes of gigantism and acromegaly are poorly …

We evaluate 3D models of human nucleoside diphosphate kinase, mouse cellular retinoic
acid binding protein I, and human eosinophil neurotoxin that were calculated by Modeller, a …

Genome sequencing projects have resulted in a rapid increase in the number of known
protein sequences. In contrast, only about one-hundredth of these sequences have been …