Role of m6A RNA methylation in cardiovascular disease

Y Qin, L Li, E Luo, J Hou, G Yan… - International …, 2020 - spandidos-publications.com
Abstract N6‑methyladenosine (m6A) is the most prevalent and abundant type of internal post‑
transcriptional RNA modification in eukaryotic cells. Multiple types of RNA, including …

m6A RNA methylation in cardiovascular diseases

S Wu, S Zhang, X Wu, X Zhou - Molecular Therapy, 2020 - cell.com
Cardiovascular diseases (CVDs) remain the leading cause of death and disability
worldwide, despite marked improvements in prevention, diagnosis, and early intervention …

N6-adenosine methylation (m6A): a promising new molecular target in hypertension and cardiovascular diseases

A Paramasivam, J Vijayashree Priyadharsini… - Hypertension …, 2020 - nature.com
To the Editor: Epitranscriptomics is an emerging field of biology, in which post-transcriptional
modifications of RNA, as a novel mechanism discovered recently, are suggested to be a vital …

RNA modification: mechanisms and therapeutic targets

L Qiu, Q Jing, Y Li, J Han - Molecular Biomedicine, 2023 - Springer
RNA modifications are dynamic and reversible chemical modifications on substrate RNA
that are regulated by specific modifying enzymes. They play important roles in the regulation …

[HTML][HTML] The critical roles of m6A modification in metabolic abnormality and cardiovascular diseases

B Zhang, H Jiang, Z Dong, A Sun, J Ge - Genes & diseases, 2021 - Elsevier
Abstract N6-methyladenosine (m6A) RNA methylation is an emerging area of epigenetics,
which is a reversible and dynamic modification mediating by 'writers'(methylase, adding …

Regulation and roles of RNA modifications in aging‐related diseases

Z Jiapaer, D Su, L Hua, HI Lehmann, P Gokulnath… - Aging …, 2022 - Wiley Online Library
With the aging of the global population, accumulating interest is focused on manipulating the
fundamental aging‐related signaling pathways to delay the physiological aging process and …

RNA modifications in cardiovascular diseases, the potential therapeutic targets

Y Wu, S Zhan, Y Xu, X Gao - Life Sciences, 2021 - Elsevier
More than one hundred RNA modifications decorate the chemical and topological properties
of these ribose nucleotides, thereby executing their biological functions through post …

RNA modification in cardiovascular disease: implications for therapeutic interventions

C Wang, X Hou, Q Guan, H Zhou, L Zhou… - … and Targeted Therapy, 2023 - nature.com
Cardiovascular disease (CVD) is the leading cause of death in the world, with a high
incidence and a youth-oriented tendency. RNA modification is ubiquitous and indispensable …

N6-methyladenosine RNA methylation in cardiovascular diseases

C Liu, L Gu, W Deng, Q Meng, N Li, G Dai… - Frontiers in …, 2022 - frontiersin.org
N6-methyladenosine (m6A) modification is the most universal and abundant post-
transcriptional modification of eukaryotic RNA and occurs mainly at the consensus motif RR …

Mechanisms of sex and gender differences in hypertension

JF Reckelhoff - Journal of Human Hypertension, 2023 - nature.com
The mechanisms that control blood pressure are multifaceted including the sympathetic
nervous system and the renin-angiotensin system leading to vasoconstriction and sodium …