Dynamic nuclear polarization for sensitivity enhancement in biomolecular solid-state NMR

T Biedenbänder, V Aladin, S Saeidpour… - Chemical …, 2022 - ACS Publications
Solid-state NMR with magic-angle spinning (MAS) is an important method in structural
biology. While NMR can provide invaluable information about local geometry on an atomic …

[HTML][HTML] Dynamic nuclear polarization for sensitivity enhancement in modern solid-state NMR

ASL Thankamony, JJ Wittmann, M Kaushik… - Progress in nuclear …, 2017 - Elsevier
The field of dynamic nuclear polarization has undergone tremendous developments and
diversification since its inception more than 6 decades ago. In this review we provide an in …

Biomolecular and biological applications of solid-state NMR with dynamic nuclear polarization enhancement

WY Chow, G De Paëpe, S Hediger - Chemical Reviews, 2022 - ACS Publications
Solid-state NMR spectroscopy (ssNMR) with magic-angle spinning (MAS) enables the
investigation of biological systems within their native context, such as lipid membranes, viral …

Green synthesis of silica and silicon nanoparticles and their biomedical and catalytic applications

N Shafiei, M Nasrollahzadeh… - Comments on Inorganic …, 2021 - Taylor & Francis
Silica and silicon nanomaterials have diverse applications in the field of drug/gene delivery,
lightweight aggregates, regenerative medicine, tissue engineering, cancer …

DNP NMR of biomolecular assemblies

K Jaudzems, T Polenova, G Pintacuda… - Journal of structural …, 2019 - Elsevier
Abstract Dynamic Nuclear Polarization (DNP) is an effective approach to alleviate the
inherently low sensitivity of solid-state NMR (ssNMR) under magic angle spinning (MAS) …

Tailoring of Polarizing Agents in the bTurea Series for Cross‐Effect Dynamic Nuclear Polarization in Aqueous Media

C Sauvée, G Casano, S Abel… - … A European Journal, 2016 - Wiley Online Library
A series of 18 nitroxide biradicals derived from bTurea has been prepared, and their
enhancement factors ɛ (1H) in cross‐effect dynamic nuclear polarization (CE DNP) NMR …

19F Dynamic Nuclear Polarization at Fast Magic Angle Spinning for NMR of HIV-1 Capsid Protein Assemblies

M Lu, M Wang, IV Sergeyev, CM Quinn… - Journal of the …, 2019 - ACS Publications
We report remarkably high, up to 100-fold, signal enhancements in 19F dynamic nuclear
polarization (DNP) magic angle spinning (MAS) spectra at 14.1 T on HIV-1 capsid protein …

Studying the conformation of a silaffin-derived pentalysine peptide embedded in bioinspired silica using solution and dynamic nuclear polarization magic-angle …

Y Geiger, HE Gottlieb, U Akbey… - journal of the …, 2016 - ACS Publications
Smart materials are created in nature at interfaces between biomolecules and solid
materials. The ability to probe the structure of functional peptides that engineer biogenic …

Structural characterization of a protein adsorbed on aluminum hydroxide adjuvant in vaccine formulation

L Cerofolini, S Giuntini, E Ravera, C Luchinat, F Berti… - npj Vaccines, 2019 - nature.com
The heterogeneous composition of vaccine formulations and the relatively low concentration
make the characterization of the protein antigens extremely challenging. Aluminum …

Lysozyme is Sterically Trapped Within the Silica Cage in Bioinspired Silica–Lysozyme Composites: A Multi-Technique Understanding of Elusive Protein–Material …

F Bruno, L Gigli, G Ferraro, A Cavallo, VK Michaelis… - Langmuir, 2022 - ACS Publications
Lysozyme is widely known to promote the formation of condensed silica networks from
solutions containing silicic acid, in a reproducible and cost-effective way. However, little is …