Addition of chemical tags on the DNA and modification of histone proteins impart a distinct
feature on chromatin architecture. With the advancement in scientific research, the key …

Reactive oxygen and nitrogen species have been implicated in diverse pathophysiological
conditions, including inflammation, neurodegenerative diseases and cancer. Accumulating …

How DNA methylation is interpreted and influences genome regulation remains largely
unknown. Proteins of the methyl-CpG-binding domain (MBD) family are primary candidates …

DNA methylation regulates many cellular processes, including embryonic development,
transcription, chromatin structure, X-chromosome inactivation, genomic imprinting and …

DNA damage is a natural hazard of life. The most common DNA lesions are base, sugar,
and single-strand break damage resulting from oxidation, alkylation, deamination, and …

The field of social and behavioral epigenetics examines the role of epigenetic modifications
to mediate the effect of psychosocial stressors on an individual's health and well-being …

Abstract Renal Cell Carcinoma (RCC) in humans is positively influenced by oxidative stress
status in kidneys. We recently reported that adaptive response to low level of chronic …

DNA methylation in mammals is a key epigenetic modification essential to normal genome
regulation and development. DNA methylation patterns are established during early …

Arsenic contamination is a significant public health issue, and kidney is one of the target
organ for arsenic‐induced adverse effects. Renal fibrosis is a well‐known pathological stage …

Retinal degenerative diseases, characterized by retinal neuronal death and severe vision
loss, affect millions of people worldwide. One of the most promising treatment methods for …