Immunomodulatory effects of radiotherapy
Radiation therapy (RT), an integral component of curative treatment for many malignancies,
can be administered via an increasing array of techniques. In this review, we summarize the …
can be administered via an increasing array of techniques. In this review, we summarize the …
ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer
Radiotherapy (RT) of colorectal cancer (CRC) can prime adaptive immunity against tumor-
associated antigen (TAA)–expressing CRC cells systemically. However, abscopal tumor …
associated antigen (TAA)–expressing CRC cells systemically. However, abscopal tumor …
[HTML][HTML] Current evidence and the potential role of proton beam therapy for hepatocellular carcinoma
SU Lee, TH Kim - Clinical and Molecular Hepatology, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death, and external
beam radiation therapy has emerged as a promising approach for managing HCC. Proton …
beam radiation therapy has emerged as a promising approach for managing HCC. Proton …
[HTML][HTML] Proton beam therapy for hepatocellular carcinoma: Multicenter prospective registry study in Japan
M Mizumoto, H Ogino, T Okumura, K Terashima… - International Journal of …, 2024 - Elsevier
Purpose A prospective multicenter registry study was started May 2016 in Japan to evaluate
the efficacy and safety of proton beam therapy (PBT) for hepatocellular carcinoma (HCC) …
the efficacy and safety of proton beam therapy (PBT) for hepatocellular carcinoma (HCC) …
Proton versus photon radiotherapy for primary hepatocellular carcinoma: a propensity-matched analysis
Background Proton radiotherapy has a dosimetric advantage over photon radiotherapy.
Many retrospective studies have shown promising results with proton radiotherapy in …
Many retrospective studies have shown promising results with proton radiotherapy in …
Predictors of radiation-induced liver disease in eastern and western patients with hepatocellular carcinoma undergoing proton beam therapy
CE Hsieh, BP Venkatesulu, CH Lee, SP Hung… - International Journal of …, 2019 - Elsevier
Purpose To identify predictors of radiation-induced liver disease (RILD) in patients with
hepatocellular carcinoma (HCC) treated with proton beam therapy (PBT). Methods This …
hepatocellular carcinoma (HCC) treated with proton beam therapy (PBT). Methods This …
[HTML][HTML] Intensity modulated proton therapy for hepatocellular carcinoma: initial clinical experience
RS Bhangoo, TC Mullikin, JB Ashman… - Advances in Radiation …, 2021 - Elsevier
Purpose Our purpose was to assess the safety and efficacy of intensity modulated proton
therapy (IMPT) for the treatment of hepatocellular carcinoma (HCC). Methods and Materials …
therapy (IMPT) for the treatment of hepatocellular carcinoma (HCC). Methods and Materials …
Dosimetric analysis and normal-tissue complication probability modeling of child-pugh score and albumin-bilirubin grade increase after hepatic irradiation
Purpose This study aimed to develop robust normal-tissue complication probability (NTCP)
models for patients with hepatocellular carcinoma treated with radiation therapy (RT) using …
models for patients with hepatocellular carcinoma treated with radiation therapy (RT) using …
Hypofractionated proton beam radiotherapy in patients with unresectable liver tumors: multi-institutional prospective results from the Proton Collaborative Group
JS Parzen, W Hartsell, J Chang, S Apisarnthanarax… - Radiation …, 2020 - Springer
Background Recent advances in radiotherapy techniques have allowed ablative doses to be
safely delivered to inoperable liver tumors. In this setting, proton beam radiotherapy (PBT) …
safely delivered to inoperable liver tumors. In this setting, proton beam radiotherapy (PBT) …
[HTML][HTML] Proton beam therapy for liver cancers
M Chuong, A Kaiser, J Molitoris… - Journal of …, 2020 - ncbi.nlm.nih.gov
Proton beam therapy (PBT) delivers less dose to nearby normal organs compared to X-ray
therapy (XRT), which is particularly relevant for treating liver cancers given that both mean …
therapy (XRT), which is particularly relevant for treating liver cancers given that both mean …