The interpretation of results on immunostained cell-block sections has to be compared with the cumulative published data derived predominantly from formalin-fixed paraffin-embedded …
C Simmons, N Miller, W Geddie, D Gianfelice… - Annals of oncology, 2009 - Elsevier
Background Decisions about systemic treatment of women with metastatic breast cancer are often based on estrogen receptor (ER), progesterone receptor (PgR), and Her2 status of the …
Semi-quantitative scoring is a method that is widely used to estimate the quantity of proteins on chromogen-labelled immunohistochemical (IHC) tissue sections. However, it suffers from …
YF Yang, YY Liao, M Yang, NF Peng, SR Xie, YF Xie - Medical Oncology, 2014 - Springer
The aim of this study was to evaluate the frequency and prognostic impact of changes in the estrogen (ER), progesterone (PR) and human epidermal growth factor receptor 2 (HER2) …
H Nitta, B Hauss-Wegrzyniak, M Lehrkamp… - Diagnostic …, 2008 - Springer
Background Human epidermal growth factor receptor 2 (HER2) fluorescence in situ hybridization (FISH) is a quantitative assay for selecting breast cancer patients for …
B Xu, J Shen, W Guo, W Zhao, Y Zhuang… - Pathology-Research and …, 2019 - Elsevier
Abstract Recently, the American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) updated the guidelines on HER2 testing for invasive breast …
Although immunohistochemistry (IHC) is a popular imaging technique, the quantitative analysis of IHC images via computer-aided methods is an emerging field that is gaining …
Cell-blocks are paraffin-embedded versions of cytology specimens comparable to the formalin-fixed paraffin-embedded (FFPE) tissue from surgical pathology specimens. They …
LC Tong, N Nelson, J Tsourigiannis… - The American journal …, 2011 - journals.lww.com
Expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) is important in predicting a response to targeted therapies in …