We present an overview of Runx involvement in regulatory mechanisms that are requisite for
fidelity of bone cell growth and differentiation, as well as for skeletal homeostasis and the …

The SpAs are a group of overlapping, chronic, inflammatory rheumatic diseases including
AS, a chronic inflammatory disease primarily affecting the SI joints. In addition to …

Injectable bone biomaterials like bone cement should be designed and fabricated with
certain biological criteria, which include: 1) recruitment and polarization of the macrophages …

Epigenetic chromatin marks restrict the ability of differentiated cells to change gene
expression programs in response to environmental cues and to transdifferentiate. Polycomb …

Objective The signs and symptoms of ankylosing spondylitis (AS) respond inadequately to
nonsteroidal antiinflammatory drugs, corticosteroids, and disease‐modifying antirheumatic …

In the present study, we explored the anti-fatigue activity and its potential mechanism of a
purified Polygonatum cyrtonema polysaccharide (PCP) on mice using weight-loaded …

Joint ankylosis is a major cause of disability in the human spondyloarthropathies. Here we
report that this process partially recapitulates embryonic endochondral bone formation in a …

Silicon is essential for bone formation. A low-silicon diet leads to bone defects, and
numerous animal models have demonstrated that silicon supplementation increases bone …

Tibial dyschondroplasia (TD) is an abnormality of the growth cartilage that occurs in
chickens and other rapidly growing avian species. This disease not only cause huge …

Objective To explore the efficacy and safety of Iguratimod (IGU) intervention in the treatment
of Ankylosing Spondylitis (AS). Methods We used computer to search literature databases …