Ethical issues in stem cell research and therapy

NMP King, J Perrin - Stem Cell Research & Therapy, 2014 - Springer
Rapid progress in biotechnology has introduced a host of pressing ethical and policy issues
pertaining to stem cell research. In this review, we provide an overview of the most …

[HTML][HTML] Accentuating the sources of mesenchymal stem cells as cellular therapy for osteoarthritis knees—a panoramic review

S Muthu, M Jeyaraman, R Jain, A Gulati… - Stem Cell …, 2021 - ncbi.nlm.nih.gov
The large economic burden on the global health care systems is due to the increasing
number of symptomatic osteoarthritis (OA) knee patients whereby accounting for greater …

Clinical trials and medical care: defining the therapeutic misconception

GE Henderson, LR Churchill, AM Davis… - PLoS …, 2007 - journals.plos.org
Clinical Trials and Medical Care: Defining the Therapeutic Misconception | PLOS Medicine Skip
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Deliberative discussion focus groups

E Rothwell, R Anderson… - Qualitative health …, 2016 - journals.sagepub.com
This article discusses a new approach for the conduct of focus groups in health research.
Identifying ways to educate and inform participants about the topic of interest prior to the …

Beyond informed consent: the therapeutic misconception and trust

I de Melo-Martin, A Ho - Journal of medical ethics, 2008 - jme.bmj.com
The therapeutic misconception has been seen as presenting an ethical problem because
failure to distinguish the aims of research participation from those receiving ordinary …

Clinical research and medical care: towards effective and complete integration

JA Sacristán - BMC medical research methodology, 2015 - Springer
Background Despite their close relationship, clinical research and medical care have
become separated by clear boundaries. The purpose of clinical research is to generate …

Therapeutic misconception in early phase gene transfer trials

GE Henderson, MM Easter, C Zimmer, NMP King… - Social science & …, 2006 - Elsevier
Many subjects in early phase clinical trials expect to benefit in some way from the research
intervention. It is understandable that people hope for improvement in their condition, no …

First-in-human trial participants: not a vulnerable population, but vulnerable nonetheless

R Dresser - Journal of Law, Medicine & Ethics, 2009 - cambridge.org
Translational science is a 21st century mission. Government officials and industry leaders
are making huge investments in an attempt to transform more basic science discoveries into …

'Well, it's the risk of the unknown… right?': a qualitative study of perceived risks and benefits of HIV cure research in the United States

K Dubé, J Taylor, L Sylla, D Evans, L Dee, A Burton… - PloS one, 2017 - journals.plos.org
Introduction Biomedical research towards an HIV cure is advancing in the United States and
elsewhere, yet little is known about perceptions of risks and benefits among potential study …

Benefit in phase 1 oncology trials: therapeutic misconception or reasonable treatment option?

FG Miller, S Joffe - Clinical Trials, 2008 - journals.sagepub.com
Novel treatments for cancer are tested initially in phase 1 trials enrolling patients with
advanced disease who have exhausted standard treatment options. Although these trials …