Translational regulation of gene expression has been implicated in numerous biological
processes. It not only enables rapid changes of cellular protein levels but is also important …

Simple Summary To produce the proteins needed for the cell to survive, the information in
the DNA is converted to a mobile form known as messenger RNA, which exits the cell …

The nuclear cap-binding complex (CBC) coordinates co-transcriptional maturation,
transport, or degradation of nascent RNA polymerase II (Pol II) transcripts. CBC with its …

Proper regulation of mRNA production in the nucleus is critical for the maintenance of
cellular homoeostasis during adaptation to internal and environmental cues. Over the past …

ARS2/SRRT is an essential eukaryotic protein that has emerged as a critical factor in the
sorting of functional from non-functional RNA polymerase II (Pol II) transcripts. Through its …

Hypoxia as a crucial pathogenesis factor usually results in huge harmful effects on cardiac
injury and dysfunction. Our previous study has uncovered the global transcriptome and …

Simple Summary We deeply characterized a frequently used mouse model of prostate
cancer and found cellular and molecular regulators of resistance against antihormonal …

Earliest microfossils provide evidence that first single cell eukaryotes appeared around 1.5
billion years ago (1). During the course of evolution, eukaryotic single cell organisms formed …