Smart magnetic drug delivery systems for the treatment of cancer

A Spoială, CI Ilie, L Motelica, D Ficai, A Semenescu… - Nanomaterials, 2023 - mdpi.com
Cancer remains the most devastating disease, being one of the main factors of death and
morbidity worldwide since ancient times. Although early diagnosis and treatment represent …

Chitosan-dextran-glycerol hydrogels loaded with iron oxide nanoparticles for wound dressing applications

C Chircov, IT Bejenaru, AI Nicoară, AC Bîrcă… - Pharmaceutics, 2022 - mdpi.com
Natural polymers have shown tremendous potential towards the development of hydrogels
with tissue regeneration properties. Among them, chitosan and dextran are polysaccharides …

Microfluidic Synthesis of Magnetite Nanoparticles for the Controlled Release of Antibiotics

C Chircov, IA Dumitru, BS Vasile, OC Oprea… - Pharmaceutics, 2023 - mdpi.com
Magnetite nanoparticles (MNPs) have been intensively studied for biomedical applications,
especially as drug delivery systems for the treatment of infections. Additionally, they are …

Covalently-bonded coating of L-arginine modified magnetic nanoparticles with dextran using co-precipitation method

B Azadpour, F Kashanian, M Habibi-Rezaei… - Materials, 2022 - mdpi.com
In this study, L-arginine (Arg) modified magnetite (Fe3O4) nanoparticles (RMNPs) were
firstly synthesized through a one-step co-precipitation method, and then these aminated …

Microfluidic Synthesis of -NH2- and -COOH-Functionalized Magnetite Nanoparticles

C Chircov, AC Bîrcă, BS Vasile, OC Oprea, KS Huang… - Nanomaterials, 2022 - mdpi.com
Microfluidics has emerged as a promising alternative for the synthesis of nanoparticles,
which ensures precise control over the synthesis parameters, high uniformity, reproducibility …

Zinc/cerium-substituted magnetite nanoparticles for biomedical applications

C Chircov, MA Mincă, AB Serban, AC Bîrcă… - International Journal of …, 2023 - mdpi.com
Numerous studies have reported the possibility of enhancing the properties of materials by
incorporating foreign elements within their crystal lattice. In this context, while magnetite has …

Magnetite microspheres for the controlled release of rosmarinic acid

C Chircov, DC Pîrvulescu, AC Bîrcă, E Andronescu… - Pharmaceutics, 2022 - mdpi.com
Since cancer incidence is constantly increasing, novel and more efficient treatment methods
that overcome the current limitations of chemotherapy are continuously explored. In this …

A comparative study of the in vitro antitumor effect of the disulfide-linked and diselenide-linked polyethylene glycol-curcumin nanoparticles

M Zhou, Q Xu, J Liu, T Zhu, Y Su, J Chu… - Journal of Dispersion …, 2024 - Taylor & Francis
Curcumin (CUR) is a natural compound extracted from turmeric (Curcuma longa), which has
been reported to be a promising anti-cancer drug in various cancers. However, poor water …

Assuring the Biofunctionalization of Silicone Covalently Bonded to Rhamnolipids: Antibiofilm Activity and Biocompatibility

M Dardouri, A Bettencourt, V Martin, FA Carvalho… - Pharmaceutics, 2022 - mdpi.com
Silicone-based medical devices composed of polydimethylsiloxane (PDMS) are widely used
all over the human body (eg, urinary stents and catheters, central venous catheters stents) …

Cerium Dioxide–Dextran Nanocomposites in the Development of a Medical Product for Wound Healing: Physical, Chemical and Biomedical Characteristics

EV Silina, NE Manturova, OS Ivanova, AE Baranchikov… - Molecules, 2024 - mdpi.com
Purpose of the study: the creation of a dextran coating on cerium oxide crystals using
different ratios of cerium and dextran to synthesize nanocomposites, and the selection of the …