Update on the pharmacology of selective inhibitors of MAO-A and MAO-B: focus on modulation of CNS monoamine neurotransmitter release

JPM Finberg - Pharmacology & therapeutics, 2014 - Elsevier
Inhibitors of monoamine oxidase (MAO) were initially used in medicine following the
discovery of their antidepressant action. Subsequently their ability to potentiate the effects of …

Pyridine alkaloids with activity in the central nervous system

SX Lin, MA Curtis, J Sperry - Bioorganic & Medicinal Chemistry, 2020 - Elsevier
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[HTML][HTML] Imaging the addicted human brain

JS Fowler, ND Volkow, CA Kassed… - Science & practice …, 2007 - ncbi.nlm.nih.gov
Modern imaging techniques enable researchers to observe drug actions and consequences
as they occur and persist in the brains of abusing and addicted individuals. This article …

Smoking, nicotine and neuropsychiatric disorders

P Dome, J Lazary, MP Kalapos, Z Rihmer - Neuroscience & Biobehavioral …, 2010 - Elsevier
Tobacco smoking is an extremely addictive and harmful form of nicotine (NIC) consumption,
but unfortunately also the most prevalent. Although disproportionately high frequencies of …

90 years of monoamine oxidase: some progress and some confusion

KF Tipton - Journal of Neural Transmission, 2018 - Springer
It would not be practical to attempt to deal with all the advances that have informed our
understanding of the behavior and functions of this enzyme over the past 90 years. This …

Monoamine oxidase and tobacco dependence

A Lewis, JH Miller, RA Lea - Neurotoxicology, 2007 - Elsevier
Tobacco smoking is a leading cause of preventable death around the world, and there are
major public health and research efforts in many countries aimed at reducing its usage …

The addition of five minor tobacco alkaloids increases nicotine-induced hyperactivity, sensitization and intravenous self-administration in rats

KJ Clemens, S Caillé, L Stinus… - International Journal of …, 2009 - academic.oup.com
Several minor tobacco alkaloids have been found to exhibit properties pharmacologically
relevant to the addictive profile of tobacco; however, little is known of their effects on a …

Genetics of nicotine dependence and pharmacotherapy

CN Lessov-Schlaggar, ML Pergadia… - Biochemical …, 2008 - Elsevier
Nicotine dependence is substantially heritable. Several regions across the genome have
been implicated in containing genes that confer liability to nicotine dependence and …

A review of monoamine oxidase (MAO) inhibitors in tobacco or tobacco smoke

SW Hong, P Teesdale-Spittle, R Page, P Truman - Neurotoxicology, 2022 - Elsevier
Tobacco smoking is reputed to be the most difficult addiction of all to give up, and nicotine
has been noted as the major addictive agent in tobacco smoke. However, research shows …

Transdermal nicotine attenuates depression symptoms in nonsmokers: a double-blind, placebo-controlled trial

FJ McClernon, FB Hiott, EC Westman, JE Rose… - …, 2006 - Springer
Rationale Despite established links between nicotine dependence and depression, little
research has examined the effects of nicotine on depression symptoms. Objective This study …