No causal effects of serum urate levels on the risk of chronic kidney disease: a Mendelian randomization study

DM Jordan, HK Choi, M Verbanck, R Topless… - PLoS …, 2019 - journals.plos.org
Background Studies have shown strong positive associations between serum urate (SU)
levels and chronic kidney disease (CKD) risk; however, whether the relation is causal …

Hyperuricemia predisposes to the onset of diabetes via promoting pancreatic β-cell death in uricase-deficient male mice

J Lu, Y He, L Cui, X Xing, Z Liu, X Li, H Zhang, H Li… - Diabetes, 2020 - Am Diabetes Assoc
Clinical studies have shown a link between hyperuricemia (HU) and diabetes, while the
exact effect of soluble serum urate on glucose metabolism remains elusive. This study aims …

[HTML][HTML] Serum urate and risk of chronic kidney disease: a mendelian randomization study using Taiwan Biobank

HM Tsao, TS Lai, YC Chang, CN Hsiung… - Mayo Clinic …, 2023 - Elsevier
Objective To evaluate the association between serum urate and risk of incident chronic
kidney disease (CKD) and to assess whether serum urate plays a causal role in CKD …

Microecological treatment of hyperuricemia using Lactobacillus from pickles

Y Xiao, C Zhang, X Zeng, Z Yuan - BMC microbiology, 2020 - Springer
Background Hyperuricemia is one of the important risk factors for gout, arteriosclerosis,
cardiovascular and cerebrovascular disease. Lactobacillus has attracted much attention due …

Serum uric acid levels and outcome during admission in acute ischaemic stroke, depending on renal function

JC Arévalo-Lorido, J Carretero-Gómez… - International Journal of …, 2018 - Taylor & Francis
Background: The relationship between serum uric acid (SUA) levels and stroke is
controversial. The discrepancies in the results could be due to the uneven setting of …

Hyperuricemia predicts an early decline in renal function among older people: a community-based cohort study

WC Tseng, YT Chen, YP Lin, SM Ou, CY Yang… - Scientific reports, 2019 - nature.com
Whether elevated serum uric acid levels (SUA) predict renal dysfunction remains
controversial in the elderly. Therefore, we investigated the association between SUA and …

食品中嘌呤的降低方法及低嘌呤产品研究进展.

刘建林, 孙学颖, 辛晓琦, 杜梅, 王倩… - Food Research & …, 2020 - search.ebscohost.com
嘌呤代谢紊乱是引起人体内诸如痛风, 肾衰竭等一系列病理表征的重要因素之一.
人体从食物中摄取的嘌呤虽少但却几乎都转变成为了诱发痛风, 肾衰竭等病症发作的有害物质 …

降尿酸乳酸菌菌株的筛选及其全基因组分析.

苗超, 张宇, 杨鑫嗾, 姜毓君… - Journal of Chinese …, 2024 - search.ebscohost.com
摘要高尿酸血症是痛风发病的生化基础, 严重威胁人体健康, 通过测定35 株乳酸菌对鸟U 和肌U
的降解能力, 筛选出4 株具有较高降解能力的乳酸菌, 对这4 株菌的菌悬液, 细胞内容物及代谢物 …

[PDF][PDF] Epidemiological studies of uric acid: a mini-review with a focus on Mendelian randomization

K Nishizawa, R Seki - Annals of Biomedical Research, 2020 - researchmap.jp
This article aims to summarize the recent epidemiological studies that have been conducted
on the potential effects of urate (uric acid) on diseases, specifically focusing on studies that …

益生菌对高尿酸血症肾功能损伤的疗效分析研究

肖源勋, 张从新, 曾鲜丽, 袁志超 - 中国全科医学, 2020 - chinagp.net
背景别嘌醇被认为是临床治疗高尿酸血症的有效药物, 但是别嘌醇对于高尿酸血症肾功能损伤
时期治疗仍存在争议, 多数学者认为别嘌醇可以有效保护肾脏, 但是由于可能会出现肾功能损伤 …