BACKGROUND: Transferrin (Tf) is an iron-binding protein that facilitates iron-uptake in cells.
Iron-loaded Tf first binds to the Tf receptor (TfR) and enters the cell through clathrin …

Endocytosis is one of the major ways cells communicate with their environment. This
process is frequently hijacked by pathogens. Endocytosis also participates in the oncogenic …

Enveloped viruses that rely on a low pH-dependent step for entry initiate infection by fusing
with acidic endosomes, whereas the entry sites for pH-independent viruses, such as HIV-1 …

Clathrin-mediated endocytosis (CME) involves the recruitment of numerous proteins to sites
on the plasma membrane with prescribed timing to mediate specific stages of the process …

Dynamin, which is encoded by three genes in mammals, is a GTPase implicated in
endocytic membrane fission. Dynamin 1 and 3 are predominantly expressed in brain …

Many cellular activities, such as cell migration, cell division, phagocytosis, and exo-
endocytosis, generate and are regulated by membrane tension gradients. Membrane …

Endocytosis is a process essential to the health and well-being of cell. It is required for the
internalisation and sorting of “cargo”—the macromolecules, proteins, receptors and lipids of …

E-cadherin plays a key role at adherens junctions between epithelial cells, but the
mechanisms controlling its assembly, maintenance, and dissociation from junctions remain …

ABSTRACT Feline herpesvirus type 1 (FHV-1) is an enveloped dsDNA virus belonging to
the Herpesviridae family and is considered one of the two primary viral etiological factors of …

Many pathogens hijack existing endocytic trafficking pathways to exert toxic effects in cells.
Dynamin controls various steps of the intoxication process used by numerous pathogenic …