Bacterial infections represent a significant health threat globally, and are responsible for the
majority of hospital-acquired infections, leading to extensive mortality and burden on global …

The emergence and wide-spread of drug-resistant bacteria including multi-drug resistant
and pan-drug resistant pathogens which are associated with considerable mortality …

Gram-positive bacteria are responsible for a broad range of infectious diseases, and the
emergency and wide spread of drug-resistant Gram-positive pathogens including MRSA …

Escherichia coli (E. coli) is the most common pathogen in both hospital and community
settings, and is capable of causing infections that can lead to serious consequences …

New pyrazole and pyrazoline derivatives have been synthesized and their ability to inhibit
ovine COX-1/COX-2 isozymes was evaluated using in vitro cyclooxygenase (COX) inhibition …

The antitumor activity of newly synthesised triazolophthalazines (L-45 analogues) 10–32
was evaluated in human hepatocellular carcinoma (HePG-2), breast cancer (MCF-7) …

The antitumor activity of newly synthesized 4-anilino-2-vinylquinazolines 8a-r was measured
comparable to sorafenib as a standard drug. The 2-vinylquinazolines 8a-r were evaluated …

Strategies for the synthesis of indole diketopiperazine alkaloids (indole DKPs) have been
described and involve three analogs of indole DKPs. The antimicrobial activity and structure …

Abstract A new series of 4, 6-disubstituted 2-(4-(dimethylamino) styryl) quinoline 4a, b–9a, b
was synthesized by the reaction of 2-(4-(dimethylamino) styryl)-6-substituted quinoline-4 …

A new series of non-carboxylic naproxen analogues, bearing a variety of ring systems, such
as oxadiazoles 3a–c and 6a–c, cycloalkanes 4a–d, cyclic imides 5a–c, and triazoles 7–9 …