Major depressive disorder (MDD) will affect one out of every five people in their lifetime and
is the leading cause of disability worldwide. Nevertheless, mechanisms associated with the …

Major depression represents a complex and prevalent psychological disease that is
characterized by persistent depressed mood, impaired cognitive function and complicated …

Exosomal microRNAs (miRNAs) have been suggested to participate in the pathogenesis of
neuropsychiatric diseases, but their role in major depressive disorder (MDD) is unknown …

Neuropsychiatric disorders and type 2 diabetes (T2D) are major public health concerns
proposed to be intimately connected. T2D is associated with increased risk of dementia …

There is increasing interest in the association between depression and the development of
metabolic diseases. Rosiglitazone, a therapeutic drug used to treat type 2 diabetes mellitus …

Major depressive disorder (MDD) is a heterogeneous psychiatric disease characterized by
persistent low mood, diminished interests, and impaired cognitive and social functions. The …

Depressive disorders constitute a set of debilitating diseases with psychological, societal,
economic and humanitarian consequences for millions of people worldwide. Scientists are …

Major depressive disorder is one of the most common neuropsychiatric diseases and it is a
global public health problem that leads to disabilities. Currently, there is a growing need to …

Background Takeda G protein–coupled receptor 5 (TGR5) is recognized as a promising
target for type 2 diabetes and metabolic syndrome; its expression has been demonstrated in …

Chronic stress is an environmental risk factor for depression and causes neuronal atrophy in
the prefrontal cortex (PFC) and other brain regions. It is still unclear about the molecular …