Inflammation‐related mechanisms in chronic kidney disease prediction, progression, and outcome

S Mihai, E Codrici, ID Popescu… - Journal of …, 2018 - Wiley Online Library
Persistent, low‐grade inflammation is now considered a hallmark feature of chronic kidney
disease (CKD), being involved in the development of all‐cause mortality of these patients …

Update on inflammation in chronic kidney disease

OM Akchurin, F Kaskel - Blood purification, 2015 - karger.com
Background: Despite recent advances in chronic kidney disease (CKD) and end-stage renal
disease (ESRD) management, morbidity and mortality in this population remain …

[HTML][HTML] International comparisons of prevalence, awareness, and treatment of pruritus in people on hemodialysis

HC Rayner, M Larkina, M Wang… - Clinical journal of the …, 2017 - journals.lww.com
Results Patients very much or extremely bothered by itching declined from 28% in 1996 to
18% in 2015. In 2012–2015, among patients nearly always or always bothered by itching …

[HTML][HTML] CKD-associated pruritus: new insights into diagnosis, pathogenesis, and management

HA Verduzco, S Shirazian - Kidney international reports, 2020 - Elsevier
Chronic kidney disease–associated pruritus (CKD-aP) is a common, troubling and in some
cases debilitating problem for patients with CKD and end-stage renal disease. Despite a …

Itch: Pathogenesis and treatment

N Sutaria, W Adawi, R Goldberg, YS Roh, J Choi… - Journal of the American …, 2022 - Elsevier
Itch pathogenesis is broadly characterized into histaminergic and nonhistaminergic
pathways and transmitted via 2 main receptor families: G protein–coupled receptors and …

Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges

S Shirazian, O Aina, Y Park, N Chowdhury… - … journal of nephrology …, 2017 - Taylor & Francis
Chronic kidney disease-associated pruritus (CKD-aP) is a distressing, often overlooked
condition in patients with CKD and end-stage renal disease. It affects~ 40% of patients with …

[HTML][HTML] Prevalence of chronic kidney disease-associated pruritus among adult dialysis patients: a meta-analysis of cross-sectional studies

X Hu, Y Sang, M Yang, X Chen, W Tang - Medicine, 2018 - journals.lww.com
Chronic kidney disease (CKD)-associated pruritus is a common adverse symptom in
patients with end-stage renal disease treated by dialysis. Herein, a systematic review and …

Pruritus and patient reported outcomes in non-dialysis CKD

N Sukul, E Speyer, C Tu, BA Bieber, Y Li… - Clinical Journal of the …, 2019 - journals.lww.com
Results Of the 5658 CKDopps patients enrolled in the United States, Brazil, and France,
3780 (67%) answered the pruritus question. The prevalence of moderate-to-extreme pruritus …

An Apriori Algorithm‐Based Association Rule Analysis to Identify Herb Combinations for Treating Uremic Pruritus Using Chinese Herbal Bath Therapy

PH Lu, JL Keng, KL Kuo, YF Wang… - Evidence‐Based …, 2020 - Wiley Online Library
Uremic pruritus (UP) is prevalent among patients with end‐stage renal disease (ESRD),
which causes severe itching and affects their quality of life. Additionally, patients experience …

Elevated interleukin 31 serum levels in hemodialysis patients are associated with uremic pruritus

AO Oweis, ALQ Firas, K Bodoor, L Heis, MA Alfaqih… - Cytokine, 2021 - Elsevier
Introduction: Uremic pruritus is a multifactorial devastating complication of renal failure,
which has a significant negative impact on patients' quality of life including medical …