The mechanisms of action of mitochondrial targeting agents in cancer: inhibiting oxidative phosphorylation and inducing apoptosis
Y Yang, Y An, M Ren, H Wang, J Bai, W Du… - Frontiers in …, 2023 - frontiersin.org
The tumor microenvironment affects the structure and metabolic function of mitochondria in
tumor cells. This process involves changes in metabolic activity, an increase in the amount …
tumor cells. This process involves changes in metabolic activity, an increase in the amount …
Spirulina platensis aqueous extracts ameliorate colonic mucosal damage and modulate gut microbiota disorder in mice with ulcerative colitis by inhibiting …
J Wang, L Su, L Zhang, J Zeng, Q Chen… - Journal of Zhejiang …, 2022 - Springer
Ulcerative colitis (UC) is a chronic and recurrent inflammatory bowel disease (IBD) that has
become a major gastroenterologic problem during recent decades. Numerous complicating …
become a major gastroenterologic problem during recent decades. Numerous complicating …
Hyperforin-mediated anticancer mechanisms in MDA-MB-231 cell line: insights into apoptotic mediator modulation and caspase activation
M Barathan, AK Zulpa, KM Vellasamy… - Journal of Taibah …, 2023 - Taylor & Francis
Breast cancer has been recorded as a frequent malignant cancer. The side effects of current
chemotherapy drugs are still a severe problem. Hence, naturally occurring phytochemicals …
chemotherapy drugs are still a severe problem. Hence, naturally occurring phytochemicals …
Inhibition of NF-κB signalling pathway by methanol extract of fruit pericarp of Garcinia gummi-gutta in inflammatory breast cancer with triple negative phenotype
KK Aathira, BJ Kariyil - 2024 - nopr.niscpr.res.in
In humans, triple negative breast cancer (TNBC) is a highly truculent form of mammary gland
cancer that connexions clinical, pathological and molecular patterns of disease with canine …
cancer that connexions clinical, pathological and molecular patterns of disease with canine …
In silico studies on cytotoxicity and antitumoral activity of acetogenins from Annona muricata L
HE Fallon Adido, CK Silva Chagas, GG Ferreira… - Frontiers in …, 2023 - frontiersin.org
As life expectancy increases, the number of people affected by cancer is increasing. The
available drugs still cause several adverse reactions, and it is important to look for less toxic …
available drugs still cause several adverse reactions, and it is important to look for less toxic …
Anticancer potential of methanol extract of seeds of Artocarpus hirsutus in human breast cancer cell lines
HM Shrirang, BJ Kariyil, R John - 2023 - nopr.niscpr.res.in
Artocarpus hirsutus, belonging to the family Moraceae, is used traditionally for the treatment
of skin problems, diarrhoea, snake bite and ulcers. In the present study, the methanol …
of skin problems, diarrhoea, snake bite and ulcers. In the present study, the methanol …
Hericium erinaceus Extract Induces Apoptosis via PI3K/AKT and RAS/MAPK Signaling Pathways in Prostate Cancer Cells
H Atmaca, Ç Çamli Pulat, S Ilhan… - Chemistry & …, 2024 - Wiley Online Library
Prostate cancer (PCa) is increasing globally, surpassing lung cancer in incidence. Despite
available treatment options, prostate cancer remains incurable. Hence, novel therapeutic …
available treatment options, prostate cancer remains incurable. Hence, novel therapeutic …
Methanol extract of Pergularia daemia (Forssk.) Chiov. leaves induce apoptosis in triple-negative breast cancer through intrinsic pathway
A GH, BJ Kariyil, AG Desai, R John, VB SV - 2023 - nopr.niscpr.res.in
Most traditional anticancer medications are ineffective in treating triple negative breast
cancer (TNBC), which has enhanced resistance to chemotherapeutic agents. Herbs …
cancer (TNBC), which has enhanced resistance to chemotherapeutic agents. Herbs …
The potential effect of Annona muricata and Cisplatin as antioxidant and antitumor in rat with liver cancer by induction of apoptosis through P13K AKT signaling …
N Zein, F Yassin, A Hassan - Biochemistry Letters, 2023 - journals.ekb.eg
Objective: The aim of this study was to investigate the effects of Cisplatin and Annona
muricata's efficacy, safety, and tolerability in treating liver cancer in rats. Method: Animals: 56 …
muricata's efficacy, safety, and tolerability in treating liver cancer in rats. Method: Animals: 56 …
Apoptosis mediated cytotoxic potential of Erythrina variegata L. stem bark in human breast carcinoma cell lines
R John, BJ Kariyil, U PTA - 2021 - nopr.niscpr.res.in
Erythrina variegata L.(Fam. Fabaceae) is traditionally known for antitumour, expectorant,
febrifuge, antibacterial and antioxidant activities. In the present study, we did cytotoxic …
febrifuge, antibacterial and antioxidant activities. In the present study, we did cytotoxic …