Characteristics and mechanisms of resorption in lumbar disc herniation
P Yu, F Mao, J Chen, X Ma, Y Dai, G Liu, F Dai… - Arthritis Research & …, 2022 - Springer
Lumbar disc herniation (LDH) can be spontaneously absorbed without surgical treatment.
However, the pathogenesis and physiological indications for predicting protrusion …
However, the pathogenesis and physiological indications for predicting protrusion …
Intervertebral disk degeneration and repair
J Dowdell, M Erwin, T Choma, A Vaccaro, J Iatridis… - …, 2017 - journals.lww.com
Intervertebral disk (IVD) degeneration is a natural progression of the aging process.
Degenerative disk disease (DDD) is a pathologic condition associated with IVD that has …
Degenerative disk disease (DDD) is a pathologic condition associated with IVD that has …
[HTML][HTML] Mesenchymal stem cells in regenerative medicine: focus on articular cartilage and intervertebral disc regeneration
Musculoskeletal disorders represent a major cause of disability and morbidity globally and
result in enormous costs for health and social care systems. Development of cell-based …
result in enormous costs for health and social care systems. Development of cell-based …
Inflammation in intervertebral disc degeneration and regeneration
M Molinos, CR Almeida, J Caldeira… - Journal of the …, 2015 - royalsocietypublishing.org
Intervertebral disc (IVD) degeneration is one of the major causes of low back pain, a
problem with a heavy economic burden, which has been increasing in prevalence as …
problem with a heavy economic burden, which has been increasing in prevalence as …
Stem cell therapy for intervertebral disc regeneration: obstacles and solutions
D Sakai, GBJ Andersson - Nature Reviews Rheumatology, 2015 - nature.com
Intervertebral disc (IVD) degeneration is frequently associated with low back and neck pain,
which accounts for disability worldwide. Despite the known outcomes of the IVD …
which accounts for disability worldwide. Despite the known outcomes of the IVD …
A review of animal models of intervertebral disc degeneration: pathophysiology, regeneration, and translation to the clinic
Lower back pain is the leading cause of disability worldwide. Discogenic pain secondary to
intervertebral disc degeneration is a significant cause of low back pain. Disc degeneration is …
intervertebral disc degeneration is a significant cause of low back pain. Disc degeneration is …
Intervertebral disc regeneration: do nutrients lead the way?
Strategies for the biological repair of intervertebral discs derive from the premise that disc
degeneration results from impaired cellular activity and, therefore, that these structures can …
degeneration results from impaired cellular activity and, therefore, that these structures can …
Degeneration and regeneration of the intervertebral disc: lessons from development
LJ Smith, NL Nerurkar, KS Choi… - Disease models & …, 2011 - journals.biologists.com
Degeneration of the intervertebral discs, a process characterized by a cascade of cellular,
biochemical, structural and functional changes, is strongly implicated as a cause of low back …
biochemical, structural and functional changes, is strongly implicated as a cause of low back …
Diversity of intervertebral disc cells: phenotype and function
The intervertebral disc (IVD) is a moderately moving joint that is located between the bony
vertebrae and provides flexibility and load transmission throughout the spinal column. The …
vertebrae and provides flexibility and load transmission throughout the spinal column. The …
Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its …
BACKGROUND CONTEXT: Degeneration and injuries of the intervertebral disc (IVD) result
in large alterations in biomechanical behaviors. Repair strategies using biomaterials can be …
in large alterations in biomechanical behaviors. Repair strategies using biomaterials can be …