Correspondence to S. Bacchetti. research in this field may render the information rapidly
outdated, we hope that the present survey of over 3500 tumour and control samples will aid …

DNA-modifying enzymes participate in various genetic functions (eg, DNA replication,
repairing, and recombination) through alternating certain DNA sequence, and the …

Telomerase is a ribonucleoprotein that synthesizes telomere repeats onto chromosome
ends and is involved in maintaining telomere length in germline tissues and in immortal and …

Recent interest in the regulation of telomerase, the enzyme that maintains chromosomal
termini, has lead to the discovery and characterization of the catalytic subunit of telomerase …

Background: The activity of the ribonucleoprotein enzyme telomerase is not detected in
normal somatic cells; thus, with each cell division, the ends of chromosomes consisting of …

The ends of vertebrate chromosomes (telomeres) are composed of many kilobases of
TTAGGGrepeats (1-4). In normal somatic cells, some of these repeats are lost during eveiy …

Helicobacter pylori are gram-negative spiral microaero-philic organisms that belong to the
Campylobacterales order, Helicobacteracea family. They are capable of colonizing the …

Human uterine endometrium undergoes a complex pattern of changes in proliferation and
secretory activity during the menstrual cycle. In the present study, telomerase activity in …

Telomerase is a cellular reverse transcriptase that helps to provide genomic stability in
highly proliferative normal, immortal, and tumor cells by maintaining the integrity of the …

Activation of telomerase and stabilization of telomeres are considered to be necessary for
immortalization of human tumor cells. In the present study, telomerase activity was detected …