The cell cycle is tightly regulated by cyclins and their catalytic moieties, the cyclin-dependent
kinases (CDKs). Cyclin D1, in association with CDK4/6, acts as a mitogenic sensor and …

The progression of cancers and neurodegenerative disorders is largely defined by a set of
molecular determinants that are either complementarily deregulated, or share remarkably …

Objective: The incidence of breast cancer continues to rise despite decades of laboratory,
epidemiological and clinical research. Breast cancer is still the leading cause of cancer …

Aramchol, an oral stearoyl‐coenzyme‐A‐desaturase‐1 inhibitor, has been shown to reduce
hepatic fat content in patients with primary nonalcoholic fatty liver disease (NAFLD); …

MicroRNAs (miRNAs) have recently come under scrutiny for their role in various age-related
diseases. Similarly, cellular senescence has been linked to disease and aging. MicroRNAs …

Purpose Owing to its genetic heterogeneity and acquired resistance, triple-negative breast
cancer (TNBC) is not responsive to single-targeted therapy, causing disproportional cancer …

Abstract Neoplasm (Glioblastoma) and Alzheimer's disease (AD) comprise two of the most
chronic psychological ailments. Glioblastoma is one of the aggressive and prevalent …

Both oxidative stress and inflammation are interdependent cellular consequences of a
biological defense system, which can fuel cancer and other pathophysiological provenience …

Hsa_circ_001988 has been identified as a tumor suppressor gene in several carcinomas.
However, its expression pattern and role in gastric cancer (GC) have still remained elusive …

This research aimed to find important genes and pathways related to cellular senescence
(CS) in diabetic foot ulcers (DFU) and to estimate the possible pathways through which CS …