Mycoplasma hyopneumoniae: from disease to vaccine development

S Simionatto, SB Marchioro, D Maes… - Veterinary …, 2013 - Elsevier
Mycoplasma hyopneumoniae is the etiological agent of swine enzootic pneumonia (EP), a
disease that affects swine production worldwide. Vaccination is the most cost-effective …

New insights on the biology of swine respiratory tract mycoplasmas from a comparative genome analysis

FM Siqueira, CE Thompson, VG Virginio… - BMC genomics, 2013 - Springer
Abstract Background Mycoplasma hyopneumoniae, Mycoplasma flocculare and
Mycoplasma hyorhinis live in swine respiratory tracts. M. flocculare, a commensal bacterium …

Unravelling the transcriptome profile of the swine respiratory tract mycoplasmas

FM Siqueira, AL Gerber, RLM Guedes, LG Almeida… - PloS one, 2014 - journals.plos.org
The swine respiratory ciliary epithelium is mainly colonized by Mycoplasma
hyopneumoniae, Mycoplasma flocculare and Mycoplasma hyorhinis. While colonization by …

Mycoplasma non-coding RNA: identification of small RNAs and targets

FM Siqueira, GL de Morais, S Higashi, LS Beier… - BMC genomics, 2016 - Springer
Abstract Background Bacterial non-coding RNAs act by base-pairing as regulatory elements
in crucial biological processes. We performed the identification of trans-encoded small …

Analysis of strand-specific RNA-seq data using machine learning reveals the structures of transcription units in Clostridium thermocellum

WC Chou, Q Ma, S Yang, S Cao… - Nucleic acids …, 2015 - academic.oup.com
Identification of transcription units (TUs) encoded in a bacterial genome is essential to
elucidation of transcriptional regulation of the organism. To gain a detailed understanding of …

Intrinsic terminators in Mycoplasma hyopneumoniae transcription

TE Fritsch, FM Siqueira, IS Schrank - BMC genomics, 2015 - Springer
Background Mycoplasma hyopneumoniae, an important pathogen of swine, exhibits a low
guanine and cytosine (GC) content genome. M. hyopneumoniae genome is organised in …

Unveiling Mycoplasma hyopneumoniae Promoters: Sequence Definition and Genomic Distribution

SS Weber, FH Sant'Anna, IS Schrank - DNA research, 2012 - academic.oup.com
Several Mycoplasma species have had their genome completely sequenced, including four
strains of the swine pathogen Mycoplasma hyopneumoniae. Nevertheless, little is known …

Repetitive Elements in Mycoplasma hyopneumoniae Transcriptional Regulation

AM Cattani, FM Siqueira, RLM Guedes, IS Schrank - PLoS One, 2016 - journals.plos.org
Transcriptional regulation, a multiple-step process, is still poorly understood in the important
pig pathogen Mycoplasma hyopneumoniae. Basic motifs like promoters and terminators …

Genome organization in Mycoplasma hyopneumoniae: identification of promoter-like sequences

FM Siqueira, S de Souto Weber, AM Cattani… - Molecular biology …, 2014 - Springer
Abstract Information related to open reading frame (ORF) organization, transcription
regulation and promoter sequence has been available for the Mycoplasma hyopneumoniae …

The influence of regulatory elements on Mycoplasma hyopneumoniae 7448 transcriptional response during oxidative stress and heat shock

G Merker Breyer, A Malvessi Cattani… - Molecular Biology …, 2022 - Springer
Background The comprehension of genome organization and gene modulation is essential
for understanding pathogens' infection mechanisms. Mycoplasma hyopneumoniae 7448 …