Immunogenic cell death (ICD) refers to an immunologically distinct process of regulated cell
death that activates, rather than suppresses, innate and adaptive immune responses. Such …

Dendritic-cells (DCs) have received considerable attention as potential targets for the
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …

Immunogenic cell death (ICD) is a type of death, which has the hallmarks of necroptosis and
apoptosis, and is best characterized in malignant diseases. Chemotherapeutics …

Cancer stem cells (CSCs) are a great challenge in the fight against cancer because these
self-renewing tumorigenic cell fractions are thought to be responsible for metastasis …

Cyclophosphamide treatment on a medium-dose, intermittent chemotherapy (MEDIC)
schedule activates both innate and adaptive immunity leading to major regression of …

Background: Molecules secreted by Trypanosoma cruzi (T. cruzi) have beneficial effects on
the immune system and can fight against cancer by inhibiting the growth of tumor cells …

Calcium is a versatile element that participates in cell signaling for a wide range of cell
processes such as death, cell cycle, division, migration, invasion, metabolism, differentiation …

Background Our previous study showed that calreticulin (CRT) promoted EGF-induced
epithelial-mesenchymal transition (EMT) in pancreatic cancer (PC) via Integrin/EGFR …

The chronic inflammatory process underlying inflammatory bowel disease (IBD), comprising
Crohn's disease and ulcerative colitis, derives from the interplay of several components in a …

Immunogenic cell death (ICD) has been proposed to be a crucial process for antitumor
immunosurveillance. ICD is characterized by the exposure and emission of Damage …