A novel population balance model to investigate the kinetics of in vitro cell proliferation: Part I. model development
In biotechnology and biomedicine reliable models of cell proliferation kinetics need to
capture the relevant phenomena taking place during the mitotic cycle. To this aim, a novel …
capture the relevant phenomena taking place during the mitotic cycle. To this aim, a novel …
A novel population balance model to investigate the kinetics of in vitro cell proliferation: Part II. numerical solution, parameters' determination, and model outcomes
Based on the general theoretical model developed in Part I of this work, a series of
numerical simulations related to the in vitro proliferation kinetics of adherent cells is here …
numerical simulations related to the in vitro proliferation kinetics of adherent cells is here …
A novel quantitative model of cell cycle progression based on cyclin-dependent kinases activity and population balances
Cell cycle regulates proliferative cell capacity under normal or pathologic conditions, and in
general it governs all in vivo/in vitro cell growth and proliferation processes. Mathematical …
general it governs all in vivo/in vitro cell growth and proliferation processes. Mathematical …
In vitro ovine articular chondrocyte proliferation: experiments and modelling
This study focuses on analysis of in vitro cultures of chondrocytes from ovine articular
cartilage. Isolated cells were seeded in Petri dishes, then expanded to confluence and …
cartilage. Isolated cells were seeded in Petri dishes, then expanded to confluence and …
Experimental analysis and modelling of in vitro HUVECs proliferation in the presence of various types of drugs
Objectives: This study focuses on experimental analysis and corresponding mathematical
simulation of in vitro HUVECs (human umbilical vein endothelial cells) proliferation in the …
simulation of in vitro HUVECs (human umbilical vein endothelial cells) proliferation in the …
Mathematical Modelling and Computational Simulation of Mammalian Cell Cycle Progression in Batch Systems
Cell cycle and its progression play a crucial role in the life of all living organisms, in tissues
and organs of animals and humans, and therefore are the subject of intense study by …
and organs of animals and humans, and therefore are the subject of intense study by …
[PDF][PDF] In vitro HUVECs proliferation in the presence of various types of drugs: Experimental analysis and mathematical modeling
The investigation of inhibitory/toxicity effect of drugs on cell proliferation is undoubtedly
useful in drug testing and development. In vitro expansion of a cell population is in general …
useful in drug testing and development. In vitro expansion of a cell population is in general …