The coexistence of a BRCA2 germline and a DICER1 somatic variant in two first-degree cousins suggests their potential synergic effect
G Del Baldo, A Mastronuzzi, S Cipri, E Agolini… - Scientific Reports, 2024 - nature.com
Cancer predisposition syndromes are recognized in about 10% of pediatric malignancies
with several genes specifically involved in a subset of pediatric tumors such as DICER1, in …
with several genes specifically involved in a subset of pediatric tumors such as DICER1, in …
Genomic scarring score predicts the response to PARP inhibitors in non-small cell lung cancer
K Tsilingiri, A Chalari, G Christopoulou… - NPJ Precision …, 2024 - nature.com
PARP inhibitors (PARPi) have shown efficacy in tumours harbouring mutations in
homologous recombination repair (HRR) genes. Somatic HRR mutations have been …
homologous recombination repair (HRR) genes. Somatic HRR mutations have been …
Coexistence of a BRCA2 germline and a DICER1 somatic variant in two first-degree young cousins: a potential cooperative role in determining cancer susceptibility?
G Del Baldo, A Mastronuzzi, S Cipri, E Agolini… - 2024 - researchsquare.com
Cancer predisposition syndromes are recognized in about 10% of pediatric malignancies
with several genes specifically involved in a subset of pediatric tumors such as DICER1, in …
with several genes specifically involved in a subset of pediatric tumors such as DICER1, in …