Importance The most common leukemia is chronic lymphocytic leukemia (CLL). Every year,
there are 15 000 new diagnoses and 5000 CLL deaths in the United States. Although …

Chronic lymphocytic leukaemia is the commonest form of leukaemia in Europe and North
America, and mainly, though not exclusively, affects older individuals. It has a very variable …

Purpose To determine the clinical significance of flow cytometric minimal residual disease
(MRD) quantification in chronic lymphocytic leukemia (CLL) in addition to pretherapeutic risk …

Purpose We conducted a randomized trial to evaluate the efficacy and safety of intravenous
alemtuzumab compared with chlorambucil in first-line treatment of chronic lymphocytic …

Of all leukemias, chronic lymphocytic leukemia (CLL) shows the highest variability in its
clinical presentation and course. CLL can present as an aggressive and life threatening …

Summation Cancer immunotherapy consists of approaches that modify the host immune
system, and/or the utilization of components of the immune system, as cancer treatment …

Purpose Chemoimmunotherapy combining fludarabine, cyclophosphamide, and rituximab
(FCR) is an active regimen for untreated patients with chronic lymphocytic leukemia (CLL) …

BACKGROUND. The prevalence of chronic lymphocytic leukemia (CLL) increases with age.
Although chemoimmunotherapy (CIT) has dramatically improved response rates in patients …

Richter syndrome (RS) represents the clinico‐pathologic transformation of chronic
lymphocytic leukaemia (CLL) to an aggressive lymphoma, most commonly diffuse large B …

Rituximab-containing regimens are becoming a therapeutic standard in chronic lymphocytic
leukemia (CLL), so that a validation of flow cytometric minimal residual disease (MRD) …