In recent years, multiple disciplines have focused on mitochondrial biology and contributed
to understanding its relevance towards adult-onset neurodegenerative disorders. These are …

Obesity is frequently associated with impairments in the social domain, and stress at puberty
can lead to long-lasting changes in visceral fat deposition and in social behaviors. However …

The incidence of cocaine abuse is increasing especially in the UK where the rates are
among the highest in Europe. In addition to its role as a psychostimulant, cocaine has …

Altered activity of the ventral pallidum (VP) underlies disrupted motivation in stress and drug
exposure. The VP is a very heterogeneous structure composed of many neuron types with …

The nucleus accumbens (NAc) is a brain hub regulating motivated behaviors, including
social competitiveness. Mitochondrial function in the NAc links anxiety with social …

Background The ability to form enduring social bonds is characteristic of human nature, and
impairments in social affiliation are central features of severe neuropsychiatric disorders …

Mitochondrial dysfunction contributes to the pathogenesis of many neurodegenerative
diseases. The mitochondrial genome encodes core respiratory chain proteins, but the vast …

Neurons in the brain have a uniquely polarized structure consisting of multiple dendrites and
a single axon generated from a cell body. Interestingly, intracellular mitochondria also show …

Mitochondrial function is required for brain energy homeostasis and neuroadaptation.
Recent studies demonstrate that cocaine affects mitochondrial dynamics and morphological …

Mitochondrial dynamics is a process that balances fusion and fission events, the latter
providing a mechanism for segregating dysfunctional mitochondria. Fission is controlled by …