Increasing evidence supports the notion that neuroinflammation plays a critical role in the
etiology of major depressive disorder (MDD), at least in a subset of patients. By virtue of their …

Purpose: Depression is one of the most prevalent, recurrent and life-threatening mental
illnesses. However, the precise mechanism underlying the disorder is not yet clearly …

There are extensive bidirectional interactions between the gut microbiota and the central
nervous system (CNS), and studies demonstrate that stressor exposure significantly alters …

Background Early childhood malnutrition affects 113 million children worldwide, impacting
health and increasing vulnerability for cognitive and behavioral disorders later in life …

Toxoplasma gondii is an obligate intracellular parasite that resides, in a latent form, in the
human central nervous system. Infection with Toxoplasma drastically alters the behaviour of …

Major depressive disorder (MDD) is a common condition that afflicts the general population
across a broad spectrum of ages and social backgrounds. MDD has been identified by the …

Objective The incidence of depression is significantly compounded by obesity. Obesity
arising from excessive intake of high-fat food provokes anxiodepressive behavior and elicits …

Major depressive disorder (MDD) is one of the leading causes of disability worldwide, and
its incidence is expected to increase. Despite tremendous efforts to understand its …

Although the literature reports a higher incidence of anxiety disorders in women, the majority
of basic research has focused on male rodents, thus resulting in a lack of knowledge on the …

Current Medicinal Chemistry Page 1 Current Medicinal Chemistry Current Medicinal
Chemistry ISSN: 0929-8673 eISSN: 1875-533X The International Journal for Timely In-depth …