Glioblastoma heterogeneity at single cell resolution

D Eisenbarth, YA Wang - Oncogene, 2023 - nature.com
Glioblastoma (GBM) is one of the deadliest types of cancer and highly refractory to
chemoradiation and immunotherapy. One of the main reasons for this resistance to therapy …

Deciphering Glioblastoma: Fundamental and Novel Insights into the Biology and Therapeutic Strategies of Gliomas

R Onciul, FM Brehar, C Toader… - Current Issues in …, 2024 - mdpi.com
Gliomas constitute a diverse and complex array of tumors within the central nervous system
(CNS), characterized by a wide range of prognostic outcomes and responses to therapeutic …

Comprehensive integrated single-cell RNA sequencing analysis of brain metastasis and glioma microenvironment: Contrasting heterogeneity landscapes

SF Sajjadi, N Salehi, M Sadeghi - Plos one, 2024 - journals.plos.org
Understanding the specific type of brain malignancy, source of brain metastasis, and
underlying transformation mechanisms can help provide better treatment and less harm to …

[HTML][HTML] Pan-cancer transcriptomic analysis of CNS tumor stroma identifies a population of perivascular fibroblasts that predict poor immunotherapy response in …

M Zarodniuk, A Steele, X Lu, J Li, M Datta - Research Square, 2023 - ncbi.nlm.nih.gov
Excessive deposition of extracellular matrix (ECM) is a hallmark of solid tumors; however, it
remains poorly understood which cellular and molecular components contribute to the …