Simple Summary Glioblastoma is a devastating malignancy that has continued to prove
resistant to a variety of therapeutics. No new systemic therapy has been approved for use …

Background and purpose Diffuse midline glioma H3K27-altered (DMG) is an aggressive,
inoperable, predominantly paediatric brain tumour. Treatment strategies are limited …

Abstract Purpose of Review Quantification and identification of cell fate remain to be the
most important step within research and diagnostic laboratories. With advances in …

Cancer stem cells (CSCs), a rare cell population in tumors, are resistant to conventional
chemotherapy and thus responsible for tumor recurrence. To screen for active compounds …

Glioblastoma (GBM) is characterized by severe hypoxic and acidic stress in an abnormal
microenvironment. Monocarboxylate transporter (MCT) 4, a pH-regulating protein, plays an …

At present, most drug screening efforts employ bulk cancer cell populations, which may lead
to selection of the more drug-resistant cancer stem cells (CSCs). However, drug screening …

The present protocol describes a standardized paradigm for rodent brain tumor resection
and tissue preservation. In clinical practice, maximal tumor resection is the standard-of-care …

In order to avoid conventional vaccines, there is an urgent need to look for new ways of
vaccine generation that can cut down the cost, time, and the need for special requirements …

Za ponovitve tumorjev in razvoj oddaljenih metastaz so odgovorne na primarno zdravljenje
odporne celice raka z izvornimi lastnostmi, ti. matične celice raka (MCR). MCR predstavljajo …