From immunotoxins to suicide toxin delivery approaches: is there a clinical opportunity?

M Ardini, R Vago, MS Fabbrini, R Ippoliti - Toxins, 2022 - mdpi.com
Suicide gene therapy is a relatively novel form of cancer therapy in which a gene coding for
enzymes or protein toxins is delivered through targeting systems such as vesicles …

[HTML][HTML] Tofacitinib to prevent anti-drug antibody formation against LMB-100 immunotoxin in patients with advanced mesothelin-expressing cancers

N Skorupan, CJ Peer, X Zhang… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Background LMB-100 is a mesothelin (MSLN)-targeting recombinant immunotoxin (iTox)
carrying a Pseudomonas exotoxin A payload that has shown promise against solid tumors …

[PDF][PDF] The role of cellular immunity in the treatment of cancer

ΒΝ Στραβοκεφάλου - 2023 - ir.lib.uth.gr
This dissertation was completed at the National Cancer Institute (NCI) of National Institutes
of Health (NIH) in the United States through a collaboration agreement with the Faculty of …

[PDF][PDF] From Immunotoxins to Suicide Toxin Delivery Approaches: Is There a Clinical Opportunity? Toxins 2022, 14, 579

M Ardini, R Vago, MS Fabbrini, R Ippoliti - 2022 - academia.edu
Suicide gene therapy is a relatively novel form of cancer therapy in which a gene coding for
enzymes or protein toxins is delivered through targeting systems such as vesicles …