Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration.
In animal models of Parkinson's disease (PD), BDNF enhances the survival of dopaminergic …

Oxidative stress is increasingly recognized as a central event contributing to the
degeneration of dopaminergic neurons in the pathogenesis of Parkinson's disease (PD) …

A failure in redox homeostasis is a common hallmark of Alzheimer's Disease (AD) and
Parkinson's Disease (PD), two age-dependent neurodegenerative disorders (NDD), causing …

The protein kinase, GSK-3, participates in diverse biological processes and is now
recognized a promising drug discovery target in treating multiple pathological conditions …

A common hallmark of age‐dependent neurodegenerative diseases is an impairment of
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …

Abstract Glycogen synthase kinase 3 (GSK-3) dysregulation plays an important role in the
pathogenesis of numerous disorders, affecting the central nervous system (CNS) …

Inhibiting glycogen synthase kinase-3 (GSK-3) activity via pharmacological intervention has
become an important strategy for treating neurodegenerative and psychiatric disorders. The …

Lithium salts have been in the therapeutic toolbox for better or worse since the 19th century,
with purported benefit in gout, hangover, insomnia, and early suggestions that lithium …

In neurons, Glycogen Synthase Kinase‐3β (GSK‐3β) has been shown to regulate various
critical processes underlying structural and functional synaptic plasticity. Mouse models with …

Dementia, a condition that frequently afflicts patients in advanced stages of Parkinson's
disease (PD), results in decreased quality of life and survival time. Nevertheless, the …