Precision medicine is a new frontier in healthcare that uses scientific methods to customize
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …

Mitral valve disease is a frequent cause of heart failure and death. Emerging evidence
indicates that the mitral valve is not a passive structure, but—even in adult life—remains …

Risk stratification scheme. Risk stratification aiming at assessing the risk of VAs and SCD in
patients with MVP, involving two phases based on the clinical and imaging context and the …

Background Recent studies reported left ventricular (LV) fibrosis in patients with primary
mitral regurgitation (MR) thought to be principally due to mitral valve prolapse (MVP) …

Objectives The aim of this study was to assess in patients with mitral valve prolapse (MVP)
mitral annular disjunction (MAD) prevalence, phenotypic characteristics, and long-term …

Objectives: This study aimed to assess the hypothesis that mitral annular disjunction (MAD)
is associated with abnormal annular dynamics due to decoupling of annular–ventricular …

Mitral regurgitation (MR) is the most prevalent valvular heart disease and, when left
untreated, it confers a poorer prognosis. Catheter-based repair therapies face some …

Transcatheter mitral valve implantation (TMVI) represents a promising approach to treating
mitral valve regurgitation in patients at increased risk of perioperative mortality. Similar to …

In light of the adverse prognosis related to severe mitral regurgitation, heart failure, or
sudden cardiac death in a subset of patients with mitral valve prolapse (MVP), identifying …

The normal mitral valve apparatus is a dynamic 3-dimensional (3D) system that allows brisk
left ventricular (LV) blood-inflow during diastole and ensures unidirectional heart pump …