Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play a key role in the
regulation of the physiological and pathological signaling within the vasculature. In …

Hydrogen sulfide in hypertension : Current Opinion in Nephrology and Hypertension Hydrogen
sulfide in hypertension : Current Opinion in Nephrology and Hypertension Log in or Register …

Background—The renin-angiotensin system (RAS) is a key player in the progression of
heart failure. Angiotensin-(1–7) is thought to modulate the activity of the RAS. Furthermore …

BACKGROUND: Essential hypertension is associated with enhanced LDL oxidation and
impaired endothelium-dependent vasodilation. The antioxidant status is linked to the nitric …

Aims Therapeutic use of sulfhydrylated inhibitor S-zofenopril has raised different hypotheses
regarding the role played by its thiol group in the beneficial clinical effects exerted compared …

Angiotensin-converting enzyme (ACE) inhibitors effectively interfere with the renin–
angiotensin system and exert various beneficial actions on vascular structure and function …

The concept of local renin–angiotensin systems has been introduced almost 20 years ago to
explain the beneficial blood pressure-independent effects of ACE inhibitors and AT1 …

Extensive research has been conducted to elucidate and substantiate the crucial role of the
Renin-Angiotensin System (RAS) in the pathogenesis of hypertension, cardiovascular …

Background Cigarette smoking may contribute to pulmonary hypertension in chronic
obstructive pulmonary disease by altering the structure and function of pulmonary vessels at …

We have studied the effect of zofenopril, a new angiotensin-converting enzyme inhibitor in
preventing cardiac injury induced by chronic doxorubicin treatment in rats. Cardiac function …