ACTN3: More than Just a Gene for Speed

C Pickering, J Kiely - Frontiers in physiology, 2017 - frontiersin.org
Over the last couple of decades, research has focused on attempting to understand the
genetic influence on sports performance. This has led to the identification of a number of …

More than a 'speed gene': ACTN3 R577X genotype, trainability, muscle damage, and the risk for injuries

J Del Coso, D Hiam, P Houweling, LM Pérez… - European journal of …, 2019 - Springer
A common null polymorphism (rs1815739; R577X) in the gene that codes for α-actinin-3
(ACTN3) has been related to different aspects of exercise performance. Individuals who are …

Sensitive periods to train general motor abilities in children and adolescents: do they exist? A critical appraisal

B Van Hooren, MDS Croix - Strength & Conditioning Journal, 2020 - journals.lww.com
Some long-term athlete development models have proposed generic sensitive periods or
“windows of opportunity” during childhood and adolescence that are optimal for training …

A genetic-based algorithm for personalized resistance training

N Jones, J Kiely, B Suraci, DJ Collins, D de Lorenzo… - Biology of sport, 2016 - termedia.pl
Association studies have identified dozens of genetic variants linked to training responses
and sport-related traits. However, no intervention studies utilizing the idea of personalised …

Genetic associations with aging muscle: a systematic review

J Pratt, C Boreham, S Ennis, AW Ryan, G De Vito - Cells, 2019 - mdpi.com
The age-related decline in skeletal muscle mass, strength and function known as
'sarcopenia'is associated with multiple adverse health outcomes, including cardiovascular …

Association of the ACTN3 R577X (rs1815739) polymorphism with elite power sports: A meta-analysis

P Tharabenjasin, N Pabalan, H Jarjanazi - PLoS One, 2019 - journals.plos.org
Objective The special status accorded to elite athletes stems from their uncommon genetic
potential to excel in world-class power sports (PS). Genetic polymorphisms have been …

Muscle Work and Its Relationship with ACE and ACTN3 Polymorphisms Are Associated with the Improvement of Explosive Strength

A Melián Ortiz, S Laguarta-Val, D Varillas-Delgado - Genes, 2021 - mdpi.com
Background: The potential influence of genetics in athletic performance allows the search for
genetic profiles associated with muscular work for the orientation of strength training and …

ACTN3, Morbidity, and Healthy Aging

C Pickering, J Kiely - Frontiers in genetics, 2018 - frontiersin.org
As human longevity increases, recent research has focused on the maintenance of optimal
health during old age. One such area of focus is that of muscle function in the elderly, with a …

[HTML][HTML] Responses to maximal strength training in different age and gender groups

HT Kittilsen, S Goleva-Fjellet, BI Freberg… - Frontiers in …, 2021 - frontiersin.org
Purpose The present study aimed to investigate the potential impact of age, gender,
baseline strength, and selected candidate polymorphisms on maximal strength training …

Mapping robust genetic variants associated with exercise responses

J Alvarez-Romero, S Voisin, N Eynon… - International journal of …, 2021 - thieme-connect.com
This review summarised robust and consistent genetic variants associated with aerobic-
related and resistance-related phenotypes. In total we highlight 12 SNPs and 7 SNPs that …