Synthesis, molecular modelling and anticancer evaluation of new pyrrolo[1,2-b]pyridazine and pyrrolo[2,1-a]phthalazine derivatives

L Popovici, RM Amarandi, II Mangalagiu… - Journal of enzyme …, 2019 - Taylor & Francis
Two new series of heterocyclic derivatives with potential anticancer activity, in which a
pyrrolo [1, 2-b] pyridazine or a pyrrolo [2, 1-a] phthalazine moiety was introduced in place of …

Design of thermochromic polynorbornene bearing spiropyran chromophore moieties: synthesis, thermal behavior and dielectric barrier discharge plasma treatment

SA Ahmed, RM Okasha, KS Khairou, TH Afifi… - Polymers, 2017 - mdpi.com
A new class of thermochromic polynorbornene with pendent spiropyran moieties has been
synthesized. Functionalization of norbornene monomers with spirobenzopyran moieties has …

Photochromism of dihydroindolizines. Part XXII: Significant effect of region B substituents on tuning the photophysical properties of photochromic dihydroindolizines …

N El Guesmi, SA Ahmed, F Maurel, II Althagafi… - … of Photochemistry and …, 2017 - Elsevier
Novel photochromic dihydroindolizines (DHIs) bearing different alkyl and cyclic alkyl ester
group (region B) were prepared via electrophilic addition of fluorene spirocyclopropenes …

[HTML][HTML] Bioactive Fluorenes. Part II. Unprecedented biologically active thiazole derivatives based-2, 7-dichlorofluorene as competent DHFR inhibitors: Design …

RI Alsantali, EM Hussein, RJ Obaid, M Morad… - Arabian Journal of …, 2020 - Elsevier
In this study, a new series of (4-(2, 7-dichloro-9H-fluoren-4-yl) thiazol-yl) acetamide
derivatives was synthesized, and the new heterocycles were completely characterized …

Synthesis and spectral investigation of novel 4-aryl-5-(aryldiazenyl) thiazole dyes festooned with fluorene moiety: Experimental and theoretical insight

N El Guesmi, AY Khormi, AS Alzahrani… - Journal of Molecular …, 2023 - Elsevier
A series of novel 4-aryl-5-(aryldiazenyl) thiazole dyes 7a-h pendant to fluorene group were
synthesized form easily accessible starting materials. The absorption spectra of the …

Photochromism of tetrahydroindolizines. Part XXV: Mechanochemical synthesis, distinctive photophysical tuning and computational studies of novel …

N El Guesmi, HM Altass, F Maurel, RJ Obaid… - … of Photochemistry and …, 2021 - Elsevier
A new mechanochemical synthetic strategy for the synthesis of novel tetrahydroindolizines
(THIs) photochromes incorporating different substituents in both regions B (ester part), and …

Photochromism of tetrahydroindolizines. Part XXVI: Mechanochemical synthesis, tunable photophysical properties and combined experimental and theoretical studies …

SA Ahmed, N El Guesmi, AAB Alsulami… - … of Photochemistry and …, 2023 - Elsevier
Herein, eighteen novel photochromic tetrahydroindolizines (THIs) have been successfully
prepared using a well-established mechanochemical synthetic approach. These products …

Photochromism of dihydroindolizines. Part XXIII: Sensitive tuning of the photophysical properties with region A and C substituents in the photochromic …

N El Guesmi, SA Ahmed, F Maurel, II Althagafi… - … of Photochemistry and …, 2018 - Elsevier
Twelve new photochromic materials based on dihydroindolizine (DHI) systems were
synthesized using mechanochemical reaction strategy in one-pot solid state reaction with …

Synthesis of 9-Substituted Fluorenols and Heteroring-fused Analogues by Intramolecular C–H Functionalization

Y Kurimoto, K Mitsudo, S Suga - Chemistry Letters, 2021 - academic.oup.com
A method for the selective synthesis of 9-substituted fluorenols (FOLs) was developed by
suppressing intermolecular cyclization and promoting intramolecular C–H functionalization …

Synthesis, Characterization and Cytotoxic Evaluation of New Pyrrolo[1,2-b]pyridazines Obtained via Mesoionic Oxazolo-Pyridazinones

BC Ivan, SF Barbuceanu, CM Hotnog, OT Olaru… - International journal of …, 2023 - mdpi.com
New pyrrolo [1, 2-b] pyridazines were synthesized by 3+ 2 cycloaddition reaction between
mesoionic oxazolo-pyridazinones and methyl/ethyl propiolate. The mesoionic compounds …