The technological utility of enzymes can be enhanced greatly by using them in organic
solvents rather than their natural aqueous reaction media. Studies over the past 15 years …

In order to exploit fully the biotechnological opportunities afforded by nonaqueous
enzymology, the issue of often drastically diminished enzymatic activity in organic solvents …

This review is concerned with lipase catalyzed synthesis of sugar fatty acid esters in water
immiscible organic solvents. Sugar esters are widely used nonionic and nontoxic …

Biocatalysis in organic solvents (OSs) has found various important applications, particularly
in organic synthesis and for the production of pharmaceuticals, flavors, and fragrances …

Biocatalysis for the synthesis of fine chemicals is highly attractive but usually requires
organic (co‐) solvents (OSs). However, native enzymes often have low activity and …

Expanding synthetic capabilities to routinely employ enzymes in organic solvents (OSs) is a
dream for protein engineers and synthetic chemists. Despite significant advances in the field …

The enantioselective esterification of ibuprofen (2-(4-iso-butylphenyl) propionic acid),
catalyzed by Candida antarctica lipase (type B), was performed in various organic solvents …

Subtilisin Carlsberg dissolved in aqueous solution is several orders of magnitude more
active than the enzyme suspended in anhydrous acetonitrile. In order to ascertain why, we …

Biocatalysis in organic solvents (OSs) enables more efficient routes to the synthesis of
various valuable chemicals. However, OSs often reduce enzymatic activity, which limits the …

Obtaining a robust and applicable enzyme for bioethanol production is a dream for
biorefinery engineers. Herein, we describe a general method to evolve an all‐round and …