Ischemia and no obstructive coronary artery disease (INOCA) developing evidence-based therapies and research agenda for the next decade

CN Bairey Merz, CJ Pepine, MN Walsh, JL Fleg… - Circulation, 2017 - Am Heart Assoc
The Cardiovascular Disease in Women Committee of the American College of Cardiology,
in conjunction with interested parties (from the National Heart, Lung, and Blood Institute …

Effect of different classes of antihypertensive drugs on endothelial function and inflammation

IVG Silva, RC de Figueiredo, DRA Rios - International journal of …, 2019 - mdpi.com
Hypertension is characterized by structural and functional changes in blood vessels that
travel with increased arterial stiffness, vascular inflammation, and endothelial dysfunction …

[HTML][HTML] Endothelial dysfunction as a target for prevention of cardiovascular disease

D Versari, E Daghini, A Virdis, L Ghiadoni… - Diabetes care, 2009 - ncbi.nlm.nih.gov
The endothelium, once considered a mere selectively permeable barrier between the
bloodstream and the outer vascular wall, is now recognized to be a crucial homeostatic …

[HTML][HTML] Vascular toxicities with VEGF inhibitor therapies–focus on hypertension and arterial thrombotic events

RM Touyz, SMS Herrmann, J Herrmann - Journal of the American Society of …, 2018 - Elsevier
The vascular endothelial growth factor (VEGF) signaling pathway (VSP) fulfills a cardinal
role in endothelial cells and its inhibition has profound cardiovascular impact. This is true not …

Assessment of flow-mediated vasodilatation (FMD) of the brachial artery: effects of technical aspects of the FMD measurement on the FMD response

ML Bots, J Westerink, TJ Rabelink… - European heart …, 2005 - academic.oup.com
Aims The ability to assess endothelial function non-invasively with B-mode ultrasound has
lead to its widespread application in a variety of studies. However, the absolute values …

Coronary microvascular dysfunction―epidemiology, pathogenesis, prognosis, diagnosis, risk factors and therapy―

C Chen, J Wei, A AlBadri, P Zarrini, CNB Merz - Circulation Journal, 2016 - jstage.jst.go.jp
Angina has traditionally been thought to be caused by obstructive coronary artery disease
(CAD). However, a substantial number of patients with angina are found to not have …

The relationship between vascular function and the autonomic nervous system

E Amiya, M Watanabe, I Komuro - Annals of vascular diseases, 2014 - jstage.jst.go.jp
Endothelial dysfunction and autonomic nervous system dysfunction are both risk factors for
atherosclerosis. There is evidence demonstrating that there is a close interrelationship …

Interactions between autonomic nervous system activity and endothelial function: a model for the development of cardiovascular disease

KF Harris, KA Matthews - Psychosomatic medicine, 2004 - journals.lww.com
Objectives Endothelial dysfunction is a new pathway in cardiovascular disease (CVD)
development. Psychosocial factors have been little studied in relation to endothelial function …

The impact of acute mental stress on vascular endothelial function: evidence, mechanisms and importance

VJ Poitras, KE Pyke - International Journal of Psychophysiology, 2013 - Elsevier
Cardiovascular disease is a principle cause of morbidity and mortality worldwide, and it has
a complex etiology that involves lifestyle factors such as psychosocial stress. Recent …

Ischemia with nonobstructive coronary artery disease: concept, assessment, and management

D Hwang, SH Park, BK Koo - JACC: Asia, 2023 - jacc.org
In daily clinical practice, physicians often encounter patients with angina or those with
evidence of myocardial ischemia from noninvasive tests but not having obstructive coronary …