Structural brain changes associated with overweight and obesity

E Gómez-Apo, A Mondragón-Maya… - Journal of …, 2021 - Wiley Online Library
Obesity is a global health problem with a broad set of comorbidities, such as malnutrition,
metabolic syndrome, diabetes, systemic hypertension, heart failure, and kidney failure. This …

The prefrontal cortex and obesity: a health neuroscience perspective

CJ Lowe, AC Reichelt, PA Hall - Trends in cognitive sciences, 2019 - cell.com
In the modern obesogenic environment, limiting calorie-dense food consumption is partially
dependent on the capacity of individuals to override visceral reactions to hyperpalatable and …

The role of leptin and adiponectin in obesity-associated cognitive decline and Alzheimer's disease

L Forny-Germano, FG De Felice… - Frontiers in …, 2019 - frontiersin.org
Cross-talk between adipose tissue and central nervous system (CNS) underlies the
increased risk of obese people to develop brain diseases such as cognitive and mood …

Association between midlife obesity and its metabolic consequences, cerebrovascular disease, and cognitive decline

F Morys, M Dadar, A Dagher - The Journal of Clinical …, 2021 - academic.oup.com
Context Chronic obesity is associated with several complications, including cognitive
impairment and dementia. However, we have only piecemeal knowledge of the mechanisms …

Associations among body mass index, cortical thickness, and executive function in children

JS Laurent, R Watts, S Adise, N Allgaier… - JAMA …, 2020 - jamanetwork.com
Importance A total of 25.7 million children in the United States are classified as overweight
or obese. Obesity is associated with deficits in executive function, which may contribute to …

Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric disorders: evidence through univariate and multivariate mega-analysis …

N Opel, A Thalamuthu, Y Milaneschi, D Grotegerd… - Molecular …, 2021 - nature.com
Emerging evidence suggests that obesity impacts brain physiology at multiple levels. Here
we aimed to clarify the relationship between obesity and brain structure using structural MRI …

The impact of obesity: a narrative review

BCC Lam, AYL Lim, SL Chan, MPS Yum… - Singapore medical …, 2023 - journals.lww.com
Obesity is a disease with a major negative impact on human health. However, people with
obesity may not perceive their weight to be a significant problem and less than half of …

Obesity and brain structure in schizophrenia–ENIGMA study in 3021 individuals

SR McWhinney, K Brosch, VD Calhoun… - Molecular …, 2022 - nature.com
Schizophrenia is frequently associated with obesity, which is linked with neurostructural
alterations. Yet, we do not understand how the brain correlates of obesity map onto the brain …

Grey matter alterations in obesity: A meta‐analysis of whole‐brain studies

MJ Herrmann, AK Tesar, J Beier, M Berg… - Obesity …, 2019 - Wiley Online Library
Obesity is a major problem in the modern world causing a higher risk for various
cerebrovascular diseases causing a profound individual and societal burden. The …

Mechanisms linking obesity and its metabolic comorbidities with cerebral grey and white matter changes

I García-García, A Michaud, MÁ Jurado… - Reviews in Endocrine …, 2022 - Springer
Obesity is a preventable risk factor for cerebrovascular disorders and it is associated with
cerebral grey and white matter changes. Specifically, individuals with obesity show …