Recent advances of imidazole-containing derivatives as anti-tubercular agents
YL Fan, XH Jin, ZP Huang, HF Yu, ZG Zeng… - European journal of …, 2018 - Elsevier
Tuberculosis still remains one of the most common, communicable, and leading deadliest
diseases known to mankind throughout the world. Drug-resistance in Mycobacterium …
diseases known to mankind throughout the world. Drug-resistance in Mycobacterium …
[HTML][HTML] Recent developments of imidazo [1, 2-a] pyridine analogues as antituberculosis agents
S Samanta, S Kumar, EK Aratikatla… - RSC Medicinal …, 2023 - pubs.rsc.org
Over the past 2000 years, tuberculosis (TB) has killed more people than any other infectious
disease. In 2021, TB claimed 1.6 million lives worldwide, making it the second leading …
disease. In 2021, TB claimed 1.6 million lives worldwide, making it the second leading …
[HTML][HTML] Recent advances in the synthesis of new benzothiazole based anti-tubercular compounds
This review highlights the recent synthetic developments of benzothiazole based anti-
tubercular compounds and their in vitro and in vivo activity. The inhibitory concentrations of …
tubercular compounds and their in vitro and in vivo activity. The inhibitory concentrations of …
Synthesis, in-silico, in vitro and DFT assessments of substituted imidazopyridine derivatives as potential antimalarials targeting hemoglobin degradation pathway
OO Ferreira, SN Mali, B Jadhav… - Journal of …, 2023 - nchr.elsevierpure.com
Malaria is a serious illness transmitted through the bite of an infected mosquito, which is
caused by a type of parasite called plasmodium and can be fatal if left untreated. Thus …
caused by a type of parasite called plasmodium and can be fatal if left untreated. Thus …
Design, synthesis and biological evaluation of imidazo [2, 1-b] thiazole and benzo [d] imidazo [2, 1-b] thiazole derivatives as Mycobacterium tuberculosis pantothenate …
In the present study, we have designed imidazo [2, 1-b] thiazole and benzo [d] imidazo [2, 1-
b] thiazole derivatives from earlier reported imidazo [1, 2-a] pyridine based Mycobacterium …
b] thiazole derivatives from earlier reported imidazo [1, 2-a] pyridine based Mycobacterium …
New structural classes of antituberculosis agents
Tuberculosis (TB), one of the deadliest diseases is shattering the health and socioeconomic
status of the society. The emergence of multidrug resistant (MDR) and extremely drug …
status of the society. The emergence of multidrug resistant (MDR) and extremely drug …
[HTML][HTML] Inhibitors of pantothenate synthetase of Mycobacterium tuberculosis–a medicinal chemist perspective
Tuberculosis (TB), one of the most prevalent infections, is on the rise today. Although there
are drugs available in the market to combat this lethal disorder, there are several …
are drugs available in the market to combat this lethal disorder, there are several …
Design, synthesis and anti-mycobacterial evaluation of imidazo [1, 2-a] pyridine analogues
YM Khetmalis, S Chitti, AU Wunnava… - RSC Medicinal …, 2022 - pubs.rsc.org
Based on the molecular hybridization strategy, thirty-four imidazo [1, 2-a] pyridine amides
(IPAs) and imidazo [1, 2-a] pyridine sulfonamides (IPSs) were designed and synthesized …
(IPAs) and imidazo [1, 2-a] pyridine sulfonamides (IPSs) were designed and synthesized …
Target-based approaches for the discovery of new antimycobacterial drugs
Highlights•The most recently studied drug targets are reviewed.•The protein–protein
interaction network was generated using STRING database.•Hits and leads were discovered …
interaction network was generated using STRING database.•Hits and leads were discovered …
New and old hot drug targets in tuberculosis
L Roberto Chiarelli, G Mori, M Esposito… - Current Medicinal …, 2016 - ingentaconnect.com
Tuberculosis is an infectious disease caused by the bacillus Mycobacterium tuberculosis.
The World Health Organization publishes global tuberculosis reports annually in order to …
The World Health Organization publishes global tuberculosis reports annually in order to …