Melioidosis

WJ Wiersinga, HS Virk, AG Torres, BJ Currie… - Nature reviews Disease …, 2018 - nature.com
Burkholderia pseudomallei is a Gram-negative environmental bacterium and the
aetiological agent of melioidosis, a life-threatening infection that is estimated to account …

Melioidosis

WJ Wiersinga, BJ Currie… - New England Journal of …, 2012 - Mass Medical Soc
Melioidosis | New England Journal of Medicine Skip to main content The New England Journal
of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical Medicine …

Pathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasion

SJ Dando, A Mackay-Sim, R Norton… - Clinical microbiology …, 2014 - Am Soc Microbiol
The brain is well protected against microbial invasion by cellular barriers, such as the blood-
brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). In addition, cells …

Melioidosis: evolving concepts in epidemiology, pathogenesis, and treatment

BJ Currie - Seminars in respiratory and critical care medicine, 2015 - thieme-connect.com
Infection with Burkholderia pseudomallei can result in asymptomatic seroconversion, a
single skin lesion that may or may not heal spontaneously, a pneumonia which can be …

[PDF][PDF] Cell culture media: a review

M Arora - Mater methods, 2013 - researchgate.net
Types of Cell Culture Media Animal cells can be cultured either using a completely natural
medium or an artificial/synthetic medium along with some natural products. Natural Media …

Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy

J Cooper-Knock, A Higginbottom, MJ Stopford… - Acta …, 2015 - Springer
GGGGCC repeat expansions of C9ORF72 represent the most common genetic variant of
amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. We and others have …

A Burkholderia type VI effector deamidates Rho GTPases to activate the pyrin inflammasome and trigger inflammation

DF Aubert, H Xu, J Yang, X Shi, W Gao, L Li, F Bisaro… - Cell host & …, 2016 - cell.com
Burkholderia cenocepacia is an opportunistic pathogen of the cystic fibrosis lung that elicits
a strong inflammatory response. B. cenocepacia employs a type VI secretion system (T6SS) …

Ribosome-inactivating proteins: Potent poisons and molecular tools

MJ Walsh, JE Dodd, GM Hautbergue - Virulence, 2013 - Taylor & Francis
Ribosome-inactivating proteins (RIPs) were first isolated over a century ago and have been
shown to be catalytic toxins that irreversibly inactivate protein synthesis. Elucidation of …

Bacteria and bacterial anticancer agents as a promising alternative for cancer therapeutics

P Baindara, SM Mandal - Biochimie, 2020 - Elsevier
Cancer is the leading cause of deaths worldwide, though significant advances have
occurred in its diagnosis and treatment. The development of resistance against …

Pathogenicity and virulence of Burkholderia pseudomallei

NM Bzdyl, CL Moran, J Bendo, M Sarkar-Tyson - Virulence, 2022 - Taylor & Francis
The soil saprophyte, Burkholderia pseudomallei, is the causative agent of melioidosis, a
disease endemic in South East Asia and northern Australia. Exposure to B. pseudomallei by …