The amphibian's spleen as a source of biomarkers for ecotoxicity assessment: Historical review and trends

E Tsukada, CC Rodrigues, JC Jacintho… - Science of The Total …, 2023 - Elsevier
Amphibians are very sensitive to many environmental changes, so these animals are
considered good bioindicator models for ecotoxicology. Given the importance of the …

Matrisomal components involved in regenerative wound healing in axolotl and Acomys: implications for biomaterial development

N Avila-Martinez, M Gansevoort, J Verbakel… - Biomaterials …, 2023 - pubs.rsc.org
Achieving regeneration in humans has been a long-standing goal of many researchers.
Whereas amphibians like the axolotl (Ambystoma mexicanum) are capable of regenerating …

Construction of the axolotl cell landscape using combinatorial hybridization sequencing at single-cell resolution

F Ye, G Zhang, WE, H Chen, C Yu, L Yang… - Nature …, 2022 - nature.com
Abstract The Mexican axolotl (Ambystoma mexicanum) is a well-established tetrapod model
for regeneration and developmental studies. Remarkably, neotenic axolotls may undergo …

Divergent influenza-like viruses of amphibians and fish support an ancient evolutionary association

R Parry, M Wille, OMH Turnbull, JL Geoghegan… - Viruses, 2020 - mdpi.com
Influenza viruses (family Orthomyxoviridae) infect a variety of vertebrates, including birds,
humans, and other mammals. Recent metatranscriptomic studies have uncovered divergent …

Experimentally induced metamorphosis in highly regenerative axolotl (ambystoma mexicanum) under constant diet restructures microbiota

T Demircan, G Ovezmyradov, B Yıldırım, İ Keskin… - Scientific Reports, 2018 - nature.com
Axolotl (Ambystoma mexicanum) is a critically endangered salamander species and a
model organism for regenerative and developmental biology. Despite life-long neoteny in …

Comparison of protein expression profile of limb regeneration between neotenic and metamorphic axolotl

M Sibai, E Altuntaş, BE Süzek, B Şahin… - Biochemical and …, 2020 - Elsevier
The axolotl (Ambystoma mexicanum) salamander, a urodele amphibian, has an exceptional
regenerative capacity to fully restore an amputated limb throughout the life-long lasting …

Lung injury in axolotl salamanders induces an organ‐wide proliferation response

TB Jensen, P Giunta, NG Schultz… - Developmental …, 2021 - Wiley Online Library
Background Ambystoma mexicanum, the axolotl salamander, is a classic model organism
used to study vertebrate regeneration. It is assumed that axolotls regenerate most tissues …

Model organisms at the heart of regeneration

EL Price, JM Vieira, PR Riley - Disease Models & …, 2019 - journals.biologists.com
Heart failure is a major cause of death worldwide owing to the inability of the adult human
heart to regenerate after a heart attack. However, many vertebrate species are capable of …

The metamorphosis of amphibian myocardium: moving to the heart of the matter

TS Filatova, I Dzhumaniiazova… - Journal of …, 2024 - journals.biologists.com
Amphibians are a classical object for physiological studies, and they are of great value for
developmental studies owing to their transition from an aquatic larval form to an adult form …

Identification of the adult hematopoietic liver as the primary reservoir for the recruitment of pro-regenerative macrophages required for salamander limb regeneration

RJ Debuque, AJ Hart, GH Johnson… - Frontiers in Cell and …, 2021 - frontiersin.org
The lack of scar-free healing and regeneration in many adult human tissues imposes severe
limitations on the recovery of function after injury. In stark contrast, salamanders can …