Artificial intelligence in cancer research and precision medicine

B Bhinder, C Gilvary, NS Madhukar, O Elemento - Cancer discovery, 2021 - AACR
Artificial intelligence (AI) is rapidly reshaping cancer research and personalized clinical
care. Availability of high-dimensionality datasets coupled with advances in high …

[PDF][PDF] Artificial intelligence for proteomics and biomarker discovery

M Mann, C Kumar, WF Zeng, MT Strauss - Cell systems, 2021 - cell.com
There is an avalanche of biomedical data generation and a parallel expansion in
computational capabilities to analyze and make sense of these data. Starting with genome …

[HTML][HTML] Machine learning techniques for personalised medicine approaches in immune-mediated chronic inflammatory diseases: applications and challenges

J Peng, EC Jury, P Dönnes, C Ciurtin - Frontiers in pharmacology, 2021 - frontiersin.org
In the past decade, the emergence of machine learning (ML) applications has led to
significant advances towards implementation of personalised medicine approaches for …

Multi-domain clinical natural language processing with MedCAT: the medical concept annotation toolkit

Z Kraljevic, T Searle, A Shek, L Roguski, K Noor… - Artificial intelligence in …, 2021 - Elsevier
Electronic health records (EHR) contain large volumes of unstructured text, requiring the
application of information extraction (IE) technologies to enable clinical analysis. We present …

[HTML][HTML] Deep learning for temporal data representation in electronic health records: A systematic review of challenges and methodologies

F Xie, H Yuan, Y Ning, MEH Ong, M Feng… - Journal of biomedical …, 2022 - Elsevier
Objective Temporal electronic health records (EHRs) contain a wealth of information for
secondary uses, such as clinical events prediction and chronic disease management …

[HTML][HTML] Precision subclassification of type 2 diabetes: a systematic review

S Misra, R Wagner, B Ozkan, M Schön… - Communications …, 2023 - nature.com
Background Heterogeneity in type 2 diabetes presentation and progression suggests that
precision medicine interventions could improve clinical outcomes. We undertook a …

[HTML][HTML] A scoping review of neurodegenerative manifestations in explainable digital phenotyping

H Alfalahi, SB Dias, AH Khandoker… - npj Parkinson's …, 2023 - nature.com
Neurologists nowadays no longer view neurodegenerative diseases, like Parkinson's and
Alzheimer's disease, as single entities, but rather as a spectrum of multifaceted symptoms …

Neighborhood contrastive learning applied to online patient monitoring

H Yèche, G Dresdner, F Locatello… - International …, 2021 - proceedings.mlr.press
Intensive care units (ICU) are increasingly looking towards machine learning for methods to
provide online monitoring of critically ill patients. In machine learning, online monitoring is …

An ensemble learning approach for enhanced classification of patients with hepatitis and cirrhosis

D Chicco, G Jurman - IEEE Access, 2021 - ieeexplore.ieee.org
Hepatitis C is an infectious disease that affects more than 70 million people worldwide, even
killing 400 thousand of them annually. To better understand this disease and its prognosis …

[HTML][HTML] Identifying and evaluating clinical subtypes of Alzheimer's disease in care electronic health records using unsupervised machine learning

N Alexander, DC Alexander, F Barkhof… - BMC Medical Informatics …, 2021 - Springer
Background Alzheimer's disease (AD) is a highly heterogeneous disease with diverse
trajectories and outcomes observed in clinical populations. Understanding this …