Initially described a century ago by William Twort and Felix d'Herelle, bacteriophages are
bacterial viruses found ubiquitously in nature, located wherever their host cells are present …

The last universal cellular ancestor (LUCA) is the most recent population of organisms from
which all cellular life on Earth descends. The reconstruction of the genome and phenotype …

The human gut microbiome plays an important role in health, but its archaeal diversity
remains largely unexplored. In the present study, we report the analysis of 1,167 …

Archaeal viruses represent one of the most mysterious parts of the global virosphere, with
many virus groups sharing no evolutionary relationship to viruses of bacteria or eukaryotes …

During the past decade, metagenomics became a method of choice for the discovery of
novel viruses. However, host assignment for uncultured viruses remains challenging …

Thermoacidophilic archaea belonging to the order Sulfolobales thrive in extreme biotopes,
such as sulfuric hot springs and ore deposits. These microorganisms have been model …

The continental subsurface houses a major portion of life's abundance and diversity, yet little
is known about viruses infecting microbes that reside there. Here, we use a combination of …

Archaea and Bacteria have evolved different defence strategies that target virtually all steps
of the viral life cycle. The diversified virion morphotypes and genome contents of archaeal …

Abstract The development of High-Throughput Sequencing (HTS) technologies is having a
major impact on the genomic analysis of viral populations. Current HTS platforms can …

Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, are
chronic, relapsing intestinal inflammatory disorders. Although the molecular mechanisms …