Protocadherins (Pcdhs) are cell adhesion molecules that belong to the cadherin
superfamily, and are subdivided into clustered (cPcdhs) and non-clustered Pcdhs (ncPcdhs) …

The protocadherins (Pcdhs), which make up the most diverse group within the cadherin
superfamily, were first discovered in the early 1990s. Data implicating the Pcdhs, including …

The∼ 70 protocadherins comprise the largest group within the cadherin superfamily. Their
diversity, the complexity of the mechanisms through which their genes are regulated, and …

The cadherin superfamily comprises a large, diverse collection of cell surface receptors that
are expressed in the nervous system throughout development and have been shown to be …

The δ-protocadherins comprise a small family of homophilic cell adhesion molecules within
the larger cadherin superfamily. They are essential for neural development as mutations in …

The connectivity amongst photoreceptors is critical to their function, as it underpins lateral
inhibition and effective translation of stimuli into neural signals. Despite much work …

In adult mammals, axon regeneration after central nervous system injury is very poor,
resulting in persistent functional loss. Enhancing the ability of axonal outgrowth may be a …

Planar cell polarity (PCP) is evolutionary conserved and play a critical role in proper tissue
development and function. During central nervous system development, PCP proteins …

Functional brain networks self-assemble during development, although the molecular basis
of network assembly is poorly understood. Protocadherin-19 (pcdh19) is a homophilic cell …

Cell migration requires spatiotemporally coordinated activities of multicomponent structures
including the actomyosin cortex, plasma membrane, adhesion complexes and the polarity …