Roles of intestinal epithelial cells in the maintenance of gut homeostasis

R Okumura, K Takeda - Experimental & molecular medicine, 2017 - nature.com
The intestine is a unique organ inhabited by a tremendous number of microorganisms.
Intestinal epithelial cells greatly contribute to the maintenance of the symbiotic relationship …

[HTML][HTML] Factors influencing the gut microbiota, inflammation, and type 2 diabetes

L Wen, A Duffy - The Journal of nutrition, 2017 - Elsevier
The gut microbiota is a complex community of bacteria residing in the intestine. Animal
models have demonstrated that several factors contribute to and can significantly alter the …

Microbiome differential abundance methods produce different results across 38 datasets

JT Nearing, GM Douglas, MG Hayes… - Nature …, 2022 - nature.com
Identifying differentially abundant microbes is a common goal of microbiome studies.
Multiple methods are used interchangeably for this purpose in the literature. Yet, there are …

Maturation of the gut microbiome during the first year of life contributes to the protective farm effect on childhood asthma

M Depner, DH Taft, PV Kirjavainen, KM Kalanetra… - Nature medicine, 2020 - nature.com
Growing up on a farm is associated with an asthma-protective effect, but the mechanisms
underlying this effect are largely unknown. In the Protection against Allergy: Study in Rural …

Meta-analysis of gut microbiome studies identifies disease-specific and shared responses

C Duvallet, SM Gibbons, T Gurry, RA Irizarry… - Nature …, 2017 - nature.com
Hundreds of clinical studies have demonstrated associations between the human
microbiome and disease, yet fundamental questions remain on how we can generalize this …

The clinical evidence for postbiotics as microbial therapeutics

A Mosca, AT Abreu Y Abreu, KA Gwee, G Ianiro… - Gut …, 2022 - Taylor & Francis
An optimally operating microbiome supports protective, metabolic, and immune functions,
but disruptions produce metabolites and toxins which can be involved in many conditions …

Microbiome in healthy skin, update for dermatologists

B Dréno, E Araviiskaia, E Berardesca… - Journal of the …, 2016 - Wiley Online Library
The skin is a complex barrier organ made of a symbiotic relationship between microbial
communities and host tissue via complex signals provided by the innate and the adaptive …

Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine learning toolbox

J Wirbel, K Zych, M Essex, N Karcher, E Kartal… - Genome biology, 2021 - Springer
The human microbiome is increasingly mined for diagnostic and therapeutic biomarkers
using machine learning (ML). However, metagenomics-specific software is scarce, and …

Dynamic distribution of gut microbiota in pigs at different growth stages: composition and contribution

Y Luo, W Ren, H Smidt, ADG Wright, B Yu… - Microbiology …, 2022 - Am Soc Microbiol
Fully understanding the dynamic distribution of the gut microbiota in pigs is essential, as gut
microorganisms play a fundamental role in physiological processes, immunity, and the …

Characterisation of early-life fecal microbiota in susceptible and healthy pigs to post-weaning diarrhoea

S Dou, P Gadonna-Widehem, V Rome, D Hamoudi… - PloS one, 2017 - journals.plos.org
Early-life microbial exposure is of particular importance to growth, immune system
development and long-lasting health. Hence, early microbiota composition is a promising …