Effects of chronic fluoxetine treatment on anxiety-and depressive-like behaviors in adolescent rodents–systematic review and meta-analysis

J Kryst, I Majcher-Maślanka, A Chocyk - Pharmacological Reports, 2022 - Springer
Background Drugs prescribed for psychiatric disorders in adolescence should be studied
very extensively since they can affect developing and thus highly plastic brain differently …

An overview of the molecular and physiological antidepressant mechanisms of physical exercise in animal models of depression

LRS de Oliveira, FSM Machado, I Rocha-Dias… - Molecular biology …, 2022 - Springer
Background Depression is a global disease that affects the physical and mental health of
people of all ages. Non-pharmacological and unconventional methods of treatment, such as …

A bird's-eye view of exercise intervention in treating depression among teenagers in the last 20 years: a bibliometric study and visualization analysis

Y You, D Wang, Y Wang, Z Li, X Ma - Frontiers in psychiatry, 2021 - frontiersin.org
Background: Exercise is medicine. Multiple studies on the effects and mechanisms of
exercise in treating depression among teenagers and adolescents have been widely …

Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of …

R Yakhkeshi, F Roshani, K Akhoundzadeh… - Physiology & Behavior, 2022 - Elsevier
There is a sex difference in vulnerability to PTSD and in response to therapeutic
interventions. Since relation between gonadal hormones and PTSD has been revealed, this …

[HTML][HTML] Anxiolytic, Antidepression, and Memory-Enhancing Effects of the Novel Instant Soup RJ6601 in the Middle-Aged of Female Rats

R Chaisanam, J Wattanathorn, W Thukham-Mee… - Foods, 2024 - mdpi.com
Due to the health benefits of polyphenols and dietary fiber in combating mental disorders,
we hypothesized that a polyphenol-and dietary fiber-enriched soup (RJ6601) would improve …

Pre-reproductive stress in adolescent female rats alters oocyte microRNA expression and offspring phenotypes: pharmacological interventions and putative …

H Zaidan, D Galiani, I Gaisler-Salomon - Translational Psychiatry, 2021 - nature.com
Pre-reproductive stress (PRS) to adolescent female rats alters anxiogenic behavior in first
(F1)-and second-generation (F2) offspring and increases mRNA expression of corticotropin …

Post-weaning social isolated flinders sensitive line rats display bio-behavioural manifestations resistant to fluoxetine: a model of treatment-resistant depression

K Mncube, M Möller, BH Harvey - Frontiers in Psychiatry, 2021 - frontiersin.org
Treatment-resistant depression (TRD) complicates the management of major depression
(MD). The underlying biology of TRD involves interplay between genetic propensity and …

Redox metabolism modulation as a mechanism in SSRI toxicity and pharmacological effects

MG Ștefan, B Kiss, AC Gutleb, F Loghin - Archives of Toxicology, 2020 - Springer
Depressive disorders are amongst the greatest mental health challenges, with an increasing
number of patients being diagnosed each year. Though it has not yet been fully elucidated …

Exercise prevents IFN-α-induced mood and cognitive dysfunction and increases BDNF expression in the rat

CK Callaghan, J Rouine, SM O'Mara - Physiology & behavior, 2017 - Elsevier
Aerobic exercise has marked effects on mood and cognition. Here, we used an interferon-
alpha (IFN-α) induced depression model to evaluate the potential efficacy of chronic …

Sildenafil, alone and in combination with imipramine or escitalopram, display antidepressant-like effects in an adrenocorticotropic hormone-induced (ACTH) rodent …

JLB Saayman, BH Harvey, G Wegener… - European Journal of …, 2024 - Elsevier
Background Major depressive disorder (MDD) represents a challenge with high prevalence
and limited effectiveness of existing treatments, particularly in cases of treatment-resistant …