The astounding world of glycans from giant viruses

I Speciale, A Notaro, C Abergel, R Lanzetta… - Chemical …, 2022 - ACS Publications
Viruses are a heterogeneous ensemble of entities, all sharing the need for a suitable host to
replicate. They are extremely diverse, varying in morphology, size, nature, and complexity of …

Chloroviruses

JL Van Etten, IV Agarkova, DD Dunigan - Viruses, 2019 - mdpi.com
Chloroviruses are large dsDNA, plaque-forming viruses that infect certain chlorella-like
green algae; the algae are normally mutualistic endosymbionts of protists and metazoans …

Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) is a UDP-dependent galactosyltransferase

JB Vicente, ACL Guerreiro, B Felgueiras, D Chapla… - Scientific Reports, 2023 - nature.com
Glycosyltransferases (GTs) are enzymes that catalyze the formation of glycosidic bonds and
hundreds of GTs have been identified so far in humans. Glycosyltransferase 8 domain …

Chloroviruses have a sweet tooth

JL Van Etten, I Agarkova, DD Dunigan, M Tonetti… - Viruses, 2017 - mdpi.com
Chloroviruses are large double-stranded DNA (dsDNA) viruses that infect certain isolates of
chlorella-like green algae. They contain up to approximately 400 protein-encoding genes …

Enzymatic glycosylation of multivalent scaffolds

P Bojarová, RR Rosencrantz, L Elling… - Chemical Society …, 2013 - pubs.rsc.org
The design of glycoclusters, glycodendrimers, glycopolymers and other complex
glycostructures that mimic the multivalent carbohydrate display on the cell surface is of …

Bacteriophages and viruses as a support for organic synthesis and combinatorial chemistry

S Ng, MR Jafari, R Derda - ACS chemical biology, 2012 - ACS Publications
Display of polypeptide on the coat proteins of bacteriophages and viruses is a powerful tool
for selection and amplification of libraries of great diversity. Chemical diversity of these …

The vaccinia virus H3 envelope protein, a major target of neutralizing antibodies, exhibits a glycosyltransferase fold and binds UDP-glucose

K Singh, AG Gittis, RK Gitti, SA Ostazeski… - Journal of …, 2016 - Am Soc Microbiol
The highly conserved H3 poxvirus protein is a major target of the human antibody response
against poxviruses and is likely a key contributor to protection against infection. Here, we …

The autonomous glycosylation of large DNA viruses

F Piacente, M Gaglianone, ME Laugieri… - International Journal of …, 2015 - mdpi.com
Glycosylation of surface molecules is a key feature of several eukaryotic viruses, which use
the host endoplasmic reticulum/Golgi apparatus to add carbohydrates to their nascent …

From small hosts come big viruses: the complete genome of a second Ostreococcus tauri virus, OtV‐1

KD Weynberg, MJ Allen, K Ashelford… - Environmental …, 2009 - Wiley Online Library
Summary Ostreococcus tauri virus (OtV‐1) is a large double‐stranded DNA virus and a
prospective member of the family Phycodnaviridae, genus Prasinovirus. OtV‐1 infects the …

Enzymatic activity of xyloglucan xylosyltransferase 5

AT Culbertson, YH Chou, AL Smith, ZT Young… - Plant …, 2016 - academic.oup.com
Xyloglucan, the most abundant hemicellulosic component of the primary cell wall of
flowering plants, is composed of a β-(1, 4)-glucan backbone decorated with d-xylosyl …