ER-phagy (reticulophagy) defines the degradation of portions of the endoplasmic reticulum
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …

Eukaryotic cells adequately control the mass and functions of organelles in various
situations. Autophagy, an intracellular degradation system, largely contributes to this …

The endoplasmic reticulum (ER) is a hotspot for many essential cellular functions. The ER
membrane is highly dynamic, which affects many cellular processes that take place within …

Three principal ER quality-control mechanisms, namely, the unfolded protein response, ER-
associated degradation (ERAD), and ER-phagy are each important for the maintenance of …

Selective degradation of the endoplasmic reticulum (ER) via autophagy (ER-phagy) is
initiated by ER-phagy receptors, which facilitate the incorporation of ER fragments into …

ER‐phagy is a selective autophagy process that targets specific regions of the endoplasmic
reticulum (ER) for removal via lysosomal degradation. During cellular stress induced by …

Conserved catabolic pathways operate to remove aberrant polypeptides from the
endoplasmic reticulum (ER), the major biosynthetic organelle of eukaryotic cells. The best …

The Hsp40, Hsp70, and Hsp90 chaperone families are ancient, highly conserved, and
critical to cellular protein homeostasis. Hsp40 chaperones can transfer their protein clients to …

Endoplasmic reticulum (ER)-phagy is crucial to regulate the function and homeostasis of the
ER via lysosomal degradation, but how it is initiated is unclear. Here we discover that Z-AAT …

Fragments of the endoplasmic reticulum (ER) are selectively delivered to the lysosome
(mammals) or vacuole (yeast) in response to starvation or the accumulation of misfolded …