The putative role of neuroinflammation in the interaction between traumatic brain injuries, sleep, pain and other neuropsychiatric outcomes: a state-of-the-art review

A Herrero Babiloni, AA Baril… - Journal of clinical …, 2023 - mdpi.com
Sleep disturbances are widely prevalent following a traumatic brain injury (TBI) and have the
potential to contribute to numerous post-traumatic physiological, psychological, and …

Melatonin and bone-related diseases: an updated mechanistic overview of current evidence and future prospects

A Bagherifard, A Hosseinzadeh, F Koosha… - Osteoporosis …, 2023 - Springer
Purpose Bone diseases account for an enormous cost burden on health systems. Bone
disorders are considered as age-dependent diseases. The aging of world population has …

Melatonin promoted osteogenesis of human periodontal ligament cells by regulating mitochondrial functions through the translocase of the outer mitochondrial …

H Sun, M Zheng, J Liu, W Fan, H He… - Journal of Periodontal …, 2023 - Wiley Online Library
Abstract Background and Objective Melatonin plays an important role in various beneficial
functions, including promoting differentiation. However, effects on osteogenic differentiation …

Agomelatine, A potential multi-target treatment alternative for insomnia, depression, and osteoporosis in postmenopausal women: A hypothetical model

A Yardimci, MR Ozdede, H Kelestimur - Frontiers in psychiatry, 2021 - frontiersin.org
Insomnia, which is associated with menopausal depression, is a common symptom of
menopause. Both symptoms have a common etiology, and can affect each other …

[HTML][HTML] The effects of agomelatine treatment on lipopolysaccharide-induced septic lung injuries in rats

D Köse, TN Yüksel, Z Halıcı, E Çadırcı… - The Eurasian Journal of …, 2021 - ncbi.nlm.nih.gov
Objective We designed an experimental model of sepsis in rats to investigate the effects of
agomelatine (AGO) on lung tissues using molecular and histopathological methods …

Relevance of sleep disturbances to orthopaedic surgery: a current concepts narrative and practical review

G Beetz, AH Babiloni, M Jodoin, C Charlebois-Plante… - JBJS, 2021 - journals.lww.com
Relevance of Sleep Disturbances to Orthopaedic Surgery: A Cu... : JBJS Relevance of Sleep
Disturbances to Orthopaedic Surgery: A Current Concepts Narrative and Practical Review …

Aprepitant: an antiemetic drug, contributes to the prevention of acute lung injury with its anti-inflammatory and antioxidant properties

D Kose, H Un, RA Ugan, Z Halici… - Journal of Pharmacy …, 2021 - academic.oup.com
Objectives We investigated, the effects of aprepitant (APRE) on the lung tissues of rats with
an experimental polymicrobial sepsis model (CLP: cecal ligation and puncture) …

Homo sapiens May Incorporate Daily Acute Cycles of “Conditioning–Deconditioning” to Maintain Musculoskeletal Integrity: Need to Integrate with Biological Clocks …

DA Hart, RF Zernicke, NG Shrive - International Journal of Molecular …, 2022 - mdpi.com
Human evolution required adaptation to the boundary conditions of Earth, including 1 g
gravity. The bipedal mobility of Homo sapiens in that gravitational field causes ground …

PROTECTIVE EFFECT OF THE RAMELTEON, A MELATONIN AGONIST, AGAINST METHOTREXATE-INDUCED BONE-TOXICITY

R Dinçer, T Baykal, DK Doğuç, E Sarman… - Medical Journal of …, 2022 - dergipark.org.tr
Objective Methotrexate (MTX) used anti-metabolite, causes bone morbidity, including growth
arrest and reduced bone mineral density. Melatonin, produced by the pineal gland, has also …

Relatório de Estágio e Monografia Intitulada “Melatonin: New Avenues for an Old Molecule”

MAR dos Santos - 2021 - search.proquest.com
Melatonina, também conhecida como N-acetil-5-metoxitriptamina, é uma hormona derivada
do triptofano produzida principalmente na glândula pineal em humanos, apesar de ser …